Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Junying Zheng; Wenjuan Ru; Jay R. Adolacion; Michael S. Spurgat; Xin Liu; Subo Yuan; Rommel X. Liang; Jianli Dong; Andrew S. Potter; S. Steven Potter; Ken Chen; Rui Chen; Navin Varadarajan; Shao-Jun Tang

doi:10.1016/j.isci.2021.102186

Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Junying Zheng, Wenjuan Ru, Jay R. Adolacion, Michael S. Spurgat, Xin Liu, Subo Yuan, Rommel X. Liang, Jianli Dong, Andrew S. Potter, S. Steven Potter, Ken Chen, Rui Chen, Navin Varadarajan, Shao-Jun Tang

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Immunology;

Original language	English (US)
Article number	102186
Journal	iScience
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.isci.2021.102186
State	Published - Mar 19 2021

Keywords

Developmental Biology
Immunology
Transcriptomics

ASJC Scopus subject areas

General

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10.1016/j.isci.2021.102186

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@article{57b7207f195e49779eef0246c92aba0c,

title = "Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia",

abstract = "Immunology;",

keywords = "Developmental Biology, Immunology, Transcriptomics",

author = "Junying Zheng and Wenjuan Ru and Adolacion, {Jay R.} and Spurgat, {Michael S.} and Xin Liu and Subo Yuan and Liang, {Rommel X.} and Jianli Dong and Potter, {Andrew S.} and Potter, {S. Steven} and Ken Chen and Rui Chen and Navin Varadarajan and Shao-Jun Tang",

note = "Funding Information: We thank members of the Tang laboratories for helpful discussions and comments. This study was supported by the National Institutes of Health R01 DA036165 (S.-J.T.), R01 NS079166 (S.-J.T.), and R01 NS095747 (S.-J.T.). Publisher Copyright: {\textcopyright} 2021 The Authors",

year = "2021",

month = mar,

day = "19",

doi = "10.1016/j.isci.2021.102186",

language = "English (US)",

volume = "24",

journal = "iScience",

issn = "2589-0042",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

AU - Zheng, Junying

AU - Ru, Wenjuan

AU - Adolacion, Jay R.

AU - Spurgat, Michael S.

AU - Liu, Xin

AU - Yuan, Subo

AU - Liang, Rommel X.

AU - Dong, Jianli

AU - Potter, Andrew S.

AU - Potter, S. Steven

AU - Chen, Ken

AU - Chen, Rui

AU - Varadarajan, Navin

AU - Tang, Shao-Jun

N1 - Funding Information: We thank members of the Tang laboratories for helpful discussions and comments. This study was supported by the National Institutes of Health R01 DA036165 (S.-J.T.), R01 NS079166 (S.-J.T.), and R01 NS095747 (S.-J.T.). Publisher Copyright: © 2021 The Authors

PY - 2021/3/19

Y1 - 2021/3/19

N2 - Immunology;

AB - Immunology;

KW - Developmental Biology

KW - Immunology

KW - Transcriptomics

UR - http://www.scopus.com/inward/record.url?scp=85101547315&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85101547315&partnerID=8YFLogxK

U2 - 10.1016/j.isci.2021.102186

DO - 10.1016/j.isci.2021.102186

M3 - Article

AN - SCOPUS:85101547315

SN - 2589-0042

VL - 24

JO - iScience

JF - iScience

IS - 3

M1 - 102186

ER -

Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Abstract

Keywords

ASJC Scopus subject areas

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