Single-voided urine metanephrine assays in screening for pheochromocytoma

N. M. Kaplan, N. J. Kramer, O. B. Holland, S. G. Sheps, C. Gomez-Sanchez

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

To facilitate the screening for pheochromocytoma, the authors have validated the use of single-voided, spot urine specimens for the determination of total metanephrines. Metanephrine excretion was found to be quite constant throughout the day and night in ten patients with essential hypertension and seven patients with pheochromocytoma. The levels in single-voided specimens were closely correlated to those in 24-hour specimens in 100 hypertensive subjects. The mean ± 2 SD metanephrine excretion in single-voided urine specimens from 500 hypertensive subjects was 0.351 ± 0.356 μg/mg of creatinine.

Original languageEnglish (US)
Pages (from-to)190-193
Number of pages4
JournalArchives of Internal Medicine
Volume137
Issue number2
DOIs
StatePublished - 1977

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Metanephrine
Pheochromocytoma
Urine
Creatinine

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Kaplan, N. M., Kramer, N. J., Holland, O. B., Sheps, S. G., & Gomez-Sanchez, C. (1977). Single-voided urine metanephrine assays in screening for pheochromocytoma. Archives of Internal Medicine, 137(2), 190-193. https://doi.org/10.1001/archinte.137.2.190

Single-voided urine metanephrine assays in screening for pheochromocytoma. / Kaplan, N. M.; Kramer, N. J.; Holland, O. B.; Sheps, S. G.; Gomez-Sanchez, C.

In: Archives of Internal Medicine, Vol. 137, No. 2, 1977, p. 190-193.

Research output: Contribution to journalArticle

Kaplan, NM, Kramer, NJ, Holland, OB, Sheps, SG & Gomez-Sanchez, C 1977, 'Single-voided urine metanephrine assays in screening for pheochromocytoma', Archives of Internal Medicine, vol. 137, no. 2, pp. 190-193. https://doi.org/10.1001/archinte.137.2.190
Kaplan, N. M. ; Kramer, N. J. ; Holland, O. B. ; Sheps, S. G. ; Gomez-Sanchez, C. / Single-voided urine metanephrine assays in screening for pheochromocytoma. In: Archives of Internal Medicine. 1977 ; Vol. 137, No. 2. pp. 190-193.
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