@article{2e28795cd6a0470fb335e172ebb3df1a,
title = "Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia",
abstract = "The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six distinct ORFs encoding the following genes: PB2 (Segment 1), PB1, (Segment 2), PA protein (Segment 3), envelope GP gene (Segment 4), the NP (Segment 5), and M-like gene (Segment 6). Phylogenetically, SINUV appears to be most closed related to viruses in the genus Thogotovirus.",
keywords = "Insect-specific viruses, Orthomyxoviridae, Sinu virus, Thogotovirus genus",
author = "Contreras-Guti{\'e}rrez, {Mar{\'i}a Ang{\'e}lica} and Nunes, {Marcio R.T.} and Hilda Guzman and Sandra Uribe and {Gallego G{\'o}mez}, {Juan Carlos} and {Suaza Vasco}, {Juan David} and Cardoso, {Jedson F.} and Popov, {Vsevolod L.} and Widen, {Steven G.} and Wood, {Thomas G.} and Nikos Vasilakis and Tesh, {Robert B.}",
note = "Funding Information: MAC is supported by a Ph.D scholarship from the Colombian Department of Science (Colciencias Convocatoria 567). The fieldwork in Colombia was supported in part by Colciencias grant 111549326198. Laboratory work in the USA was funded in part by NIH grant R24 AI120942. We also acknowledge the help of Sandro Patroca da Silva in doing the Boxplot analysis and Richard Hoyos for mosquito collections.",
year = "2017",
month = jan,
day = "15",
doi = "10.1016/j.virol.2016.11.014",
language = "English (US)",
volume = "501",
pages = "166--175",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
}