Skin rash and microscopic hematuria in a 10-year-old Caucasian male

Zheng Cao, Rejwi A. Dahal, Ping Wang, John R. Petersen, Anthony Okorodudu

Research output: Contribution to journalArticle

Abstract

Objective: Henoch-Schonlein purpura (HSP) is an acute, systemic, vasculitis with IgA-dominant immune deposits. With the emphasis on educational value of HSP, which is the most common form of vasculitis in children, we report an actual case from a 10-year-old boy. Method: The patient presented with the chief complaint of a skin rash. His illness history, family medical history, physical examination, and relevant laboratory findings were summarized, followed by a question and possible answer format discussion. Results and Conclusion: With the significant elevation of red blood cells in his urine and moderate to severe deposition of IgA in kidney biopsy, the patient was diagnosed with HSP nephritis. Renal symptoms, such as proteinuria and hematuria, are mostly the last to develop and determine the long-term prognosis in HSP patients. The patient is currently undergoing steroid treatment, which is the primary intervention for HSP as it spontaneously resolves in most of affected children.

Original languageEnglish (US)
Pages (from-to)158-162
Number of pages5
JournalLaboratory Medicine
Volume47
Issue number2
DOIs
StatePublished - 2016

Fingerprint

Schoenlein-Henoch Purpura
Hematuria
Exanthema
Immunoglobulin A
Skin
Biopsy
Blood
Deposits
Steroids
Cells
Medical History Taking
Kidney
Systemic Vasculitis
Nephritis
Vasculitis
Proteinuria
Physical Examination
Erythrocytes
History
Urine

Keywords

  • Arthritis
  • Hematuria
  • Henoch-Schonlein purpura (HSP)
  • IgA
  • Skin rash
  • Vasculitis

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Skin rash and microscopic hematuria in a 10-year-old Caucasian male. / Cao, Zheng; Dahal, Rejwi A.; Wang, Ping; Petersen, John R.; Okorodudu, Anthony.

In: Laboratory Medicine, Vol. 47, No. 2, 2016, p. 158-162.

Research output: Contribution to journalArticle

Cao, Zheng ; Dahal, Rejwi A. ; Wang, Ping ; Petersen, John R. ; Okorodudu, Anthony. / Skin rash and microscopic hematuria in a 10-year-old Caucasian male. In: Laboratory Medicine. 2016 ; Vol. 47, No. 2. pp. 158-162.
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