Small and wide angle backscattering from rabbit cornea measured ex vivo by optical coherence tomography and confocal microscopy

Alexander I. Kholodnykh, Sergey Yu Treschev, Massoud Motamedi

    Research output: Contribution to journalConference articlepeer-review

    Abstract

    Results of comparative ex vivo measurements of backscattering from rabbit cornea made by optical coherency tomography and confocal microscopy strongly suggests the existence of small angle backscattering from the cornea. Apparently, this is associated with a zero order peak of diffraction on the corneal fibril "lattice" structure, which was first suggested by D. Maurice in 1957 as a physical basis of corneal transparency. By using water suspension of polystyrene spheres as a scattering standard, absolute values of backscattering coefficients of normally hydrated cornea for wide and small angle backscattering and degree of fibrils arrangement could be estimated.

    Original languageEnglish (US)
    Article number53
    Pages (from-to)318-324
    Number of pages7
    JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume5690
    DOIs
    StatePublished - Jul 21 2005
    EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX - San Jose, CA, United States
    Duration: Jan 23 2005Jan 26 2005

    Keywords

    • Corneal backscattering
    • Corneal hydration control
    • Fibrillar order
    • Noninvasive monitoring
    • OCT

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

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