Smallpox and pregnancy

From eradicated disease to bioterrorist threat

Victor R. Suarez, Gary Hankins

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Health care personnel must be prepared for the threat of bioterrorism. Our objective is to educate primary care providers, obstetricians in particular, in the prevention, diagnosis, and treatment of smallpox. Smallpox poses a particularly serious threat because of its high case-fatality rate in unvaccinated populations (no one younger than 25 years has been vaccinated, and older persons have little remaining residual immunity). Routine nonemergency smallpox vaccination is restricted to laboratory staff working with smallpox-related viruses. Under these circumstances, contraindications to vaccination are pregnancy, immunodeficiency, exfoliative skin conditions (eczema), and allergy to vaccine components. In case of an intentional release of the smallpox virus, those directly exposed and their close contacts must be vaccinated and isolated. Under such emergency circumstances, pregnant women exposed to the variola virus should be vaccinated because of the lethality of the disease during pregnancy. Currently, there is a limited supply of vaccine available.

Original languageEnglish (US)
Pages (from-to)87-93
Number of pages7
JournalObstetrics and Gynecology
Volume100
Issue number1
DOIs
StatePublished - 2002

Fingerprint

Variola virus
Smallpox
Pregnancy
Vaccination
Vaccines
Bioterrorism
Eczema
Health Personnel
Pregnant Women
Immunity
Primary Health Care
Hypersensitivity
Emergencies
Delivery of Health Care
Skin
Mortality
Population
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Smallpox and pregnancy : From eradicated disease to bioterrorist threat. / Suarez, Victor R.; Hankins, Gary.

In: Obstetrics and Gynecology, Vol. 100, No. 1, 2002, p. 87-93.

Research output: Contribution to journalArticle

Suarez, Victor R. ; Hankins, Gary. / Smallpox and pregnancy : From eradicated disease to bioterrorist threat. In: Obstetrics and Gynecology. 2002 ; Vol. 100, No. 1. pp. 87-93.
@article{35ba93e8417443159e23a2833be2db05,
title = "Smallpox and pregnancy: From eradicated disease to bioterrorist threat",
abstract = "Health care personnel must be prepared for the threat of bioterrorism. Our objective is to educate primary care providers, obstetricians in particular, in the prevention, diagnosis, and treatment of smallpox. Smallpox poses a particularly serious threat because of its high case-fatality rate in unvaccinated populations (no one younger than 25 years has been vaccinated, and older persons have little remaining residual immunity). Routine nonemergency smallpox vaccination is restricted to laboratory staff working with smallpox-related viruses. Under these circumstances, contraindications to vaccination are pregnancy, immunodeficiency, exfoliative skin conditions (eczema), and allergy to vaccine components. In case of an intentional release of the smallpox virus, those directly exposed and their close contacts must be vaccinated and isolated. Under such emergency circumstances, pregnant women exposed to the variola virus should be vaccinated because of the lethality of the disease during pregnancy. Currently, there is a limited supply of vaccine available.",
author = "Suarez, {Victor R.} and Gary Hankins",
year = "2002",
doi = "10.1016/S0029-7844(02)02048-3",
language = "English (US)",
volume = "100",
pages = "87--93",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Smallpox and pregnancy

T2 - From eradicated disease to bioterrorist threat

AU - Suarez, Victor R.

AU - Hankins, Gary

PY - 2002

Y1 - 2002

N2 - Health care personnel must be prepared for the threat of bioterrorism. Our objective is to educate primary care providers, obstetricians in particular, in the prevention, diagnosis, and treatment of smallpox. Smallpox poses a particularly serious threat because of its high case-fatality rate in unvaccinated populations (no one younger than 25 years has been vaccinated, and older persons have little remaining residual immunity). Routine nonemergency smallpox vaccination is restricted to laboratory staff working with smallpox-related viruses. Under these circumstances, contraindications to vaccination are pregnancy, immunodeficiency, exfoliative skin conditions (eczema), and allergy to vaccine components. In case of an intentional release of the smallpox virus, those directly exposed and their close contacts must be vaccinated and isolated. Under such emergency circumstances, pregnant women exposed to the variola virus should be vaccinated because of the lethality of the disease during pregnancy. Currently, there is a limited supply of vaccine available.

AB - Health care personnel must be prepared for the threat of bioterrorism. Our objective is to educate primary care providers, obstetricians in particular, in the prevention, diagnosis, and treatment of smallpox. Smallpox poses a particularly serious threat because of its high case-fatality rate in unvaccinated populations (no one younger than 25 years has been vaccinated, and older persons have little remaining residual immunity). Routine nonemergency smallpox vaccination is restricted to laboratory staff working with smallpox-related viruses. Under these circumstances, contraindications to vaccination are pregnancy, immunodeficiency, exfoliative skin conditions (eczema), and allergy to vaccine components. In case of an intentional release of the smallpox virus, those directly exposed and their close contacts must be vaccinated and isolated. Under such emergency circumstances, pregnant women exposed to the variola virus should be vaccinated because of the lethality of the disease during pregnancy. Currently, there is a limited supply of vaccine available.

UR - http://www.scopus.com/inward/record.url?scp=0036299370&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036299370&partnerID=8YFLogxK

U2 - 10.1016/S0029-7844(02)02048-3

DO - 10.1016/S0029-7844(02)02048-3

M3 - Article

VL - 100

SP - 87

EP - 93

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 1

ER -