Sociodemographic Disparities in Cure-Intended Treatment in Localized Prostate Cancer

Jude K.A. des Bordes, David Lopez, Michael D. Swartz, Robert J. Volk

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: Disparities in prostate cancer (PCa) morbidity and mortality occur across various populations. We investigated the sociodemographic correlates of treatment and disparities in the application of cure-intended (i.e., radical prostatectomy [RP], radiation therapy [RT]) treatment strategies in localized PCa among Texas residents diagnosed with PCa. Methods: We analyzed data from the Texas Cancer Registry on men diagnosed with stage T1 or T2 PCa between 2004 and 2009. Multinomial logistic regression analysis was used to explore independent associations between cure-intended treatment modalities and sociodemographic characteristics (age, race/ethnicity, socioeconomic status [SES], and geographic location (rural versus urban)) using patients who did not receive definitive treatment as comparison group. Results: Of 46,971 patients with available treatment data, age-adjusted treatment rates were 39.1% RP, 30.7% RT, and 30.2% for all other non-curative modalities. Compared to patients under 60 years, those ≥60 were less likely to receive RP, patients between 60 and 80 years were more likely to undergo RT, while those 80 years or older were less likely. Non-Hispanic blacks (OR =0.55, 95% CI, 0.50–0.59) and Hispanics (OR = 0.68, 95%CI, 0.62–0.74) were less likely to receive RP compared with whites. Hispanics were significantly less likely to receive RT (OR = 0.78, 95%CI, 0.72–0.85) than blacks and whites. People of low SES were 35% (OR = 0.65, 95%CI, 0.60–0.69) and 15% (OR = 0.85, 95%CI, 0.79–0.90) less likely to receive RP and RT, respectively, compared with those of high SES. Rural-urban status was not associated with cure-intended treatment. Conclusion: Potential sociodemographic disparities exist in the application of cure-intended treatment in localized prostate cancer in Texas particularly in race/ethnicity and SES.

Original languageEnglish (US)
Pages (from-to)104-110
Number of pages7
JournalJournal of Racial and Ethnic Health Disparities
Volume5
Issue number1
DOIs
StatePublished - Feb 1 2018
Externally publishedYes

Fingerprint

Prostatic Neoplasms
cancer
Prostatectomy
social status
Radiotherapy
Social Class
Therapeutics
ethnicity
Hispanic Americans
Geographic Locations
morbidity
regression analysis
mortality
logistics
resident
Registries
Logistic Models
Regression Analysis
Morbidity
Mortality

Keywords

  • Demographic factors
  • Prostate cancer
  • Treatment disparities
  • Treatment modalities

ASJC Scopus subject areas

  • Health(social science)
  • Anthropology
  • Sociology and Political Science
  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Sociodemographic Disparities in Cure-Intended Treatment in Localized Prostate Cancer. / des Bordes, Jude K.A.; Lopez, David; Swartz, Michael D.; Volk, Robert J.

In: Journal of Racial and Ethnic Health Disparities, Vol. 5, No. 1, 01.02.2018, p. 104-110.

Research output: Contribution to journalArticle

des Bordes, Jude K.A. ; Lopez, David ; Swartz, Michael D. ; Volk, Robert J. / Sociodemographic Disparities in Cure-Intended Treatment in Localized Prostate Cancer. In: Journal of Racial and Ethnic Health Disparities. 2018 ; Vol. 5, No. 1. pp. 104-110.
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abstract = "Purpose: Disparities in prostate cancer (PCa) morbidity and mortality occur across various populations. We investigated the sociodemographic correlates of treatment and disparities in the application of cure-intended (i.e., radical prostatectomy [RP], radiation therapy [RT]) treatment strategies in localized PCa among Texas residents diagnosed with PCa. Methods: We analyzed data from the Texas Cancer Registry on men diagnosed with stage T1 or T2 PCa between 2004 and 2009. Multinomial logistic regression analysis was used to explore independent associations between cure-intended treatment modalities and sociodemographic characteristics (age, race/ethnicity, socioeconomic status [SES], and geographic location (rural versus urban)) using patients who did not receive definitive treatment as comparison group. Results: Of 46,971 patients with available treatment data, age-adjusted treatment rates were 39.1{\%} RP, 30.7{\%} RT, and 30.2{\%} for all other non-curative modalities. Compared to patients under 60 years, those ≥60 were less likely to receive RP, patients between 60 and 80 years were more likely to undergo RT, while those 80 years or older were less likely. Non-Hispanic blacks (OR =0.55, 95{\%} CI, 0.50–0.59) and Hispanics (OR = 0.68, 95{\%}CI, 0.62–0.74) were less likely to receive RP compared with whites. Hispanics were significantly less likely to receive RT (OR = 0.78, 95{\%}CI, 0.72–0.85) than blacks and whites. People of low SES were 35{\%} (OR = 0.65, 95{\%}CI, 0.60–0.69) and 15{\%} (OR = 0.85, 95{\%}CI, 0.79–0.90) less likely to receive RP and RT, respectively, compared with those of high SES. Rural-urban status was not associated with cure-intended treatment. Conclusion: Potential sociodemographic disparities exist in the application of cure-intended treatment in localized prostate cancer in Texas particularly in race/ethnicity and SES.",
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AU - des Bordes, Jude K.A.

AU - Lopez, David

AU - Swartz, Michael D.

AU - Volk, Robert J.

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N2 - Purpose: Disparities in prostate cancer (PCa) morbidity and mortality occur across various populations. We investigated the sociodemographic correlates of treatment and disparities in the application of cure-intended (i.e., radical prostatectomy [RP], radiation therapy [RT]) treatment strategies in localized PCa among Texas residents diagnosed with PCa. Methods: We analyzed data from the Texas Cancer Registry on men diagnosed with stage T1 or T2 PCa between 2004 and 2009. Multinomial logistic regression analysis was used to explore independent associations between cure-intended treatment modalities and sociodemographic characteristics (age, race/ethnicity, socioeconomic status [SES], and geographic location (rural versus urban)) using patients who did not receive definitive treatment as comparison group. Results: Of 46,971 patients with available treatment data, age-adjusted treatment rates were 39.1% RP, 30.7% RT, and 30.2% for all other non-curative modalities. Compared to patients under 60 years, those ≥60 were less likely to receive RP, patients between 60 and 80 years were more likely to undergo RT, while those 80 years or older were less likely. Non-Hispanic blacks (OR =0.55, 95% CI, 0.50–0.59) and Hispanics (OR = 0.68, 95%CI, 0.62–0.74) were less likely to receive RP compared with whites. Hispanics were significantly less likely to receive RT (OR = 0.78, 95%CI, 0.72–0.85) than blacks and whites. People of low SES were 35% (OR = 0.65, 95%CI, 0.60–0.69) and 15% (OR = 0.85, 95%CI, 0.79–0.90) less likely to receive RP and RT, respectively, compared with those of high SES. Rural-urban status was not associated with cure-intended treatment. Conclusion: Potential sociodemographic disparities exist in the application of cure-intended treatment in localized prostate cancer in Texas particularly in race/ethnicity and SES.

AB - Purpose: Disparities in prostate cancer (PCa) morbidity and mortality occur across various populations. We investigated the sociodemographic correlates of treatment and disparities in the application of cure-intended (i.e., radical prostatectomy [RP], radiation therapy [RT]) treatment strategies in localized PCa among Texas residents diagnosed with PCa. Methods: We analyzed data from the Texas Cancer Registry on men diagnosed with stage T1 or T2 PCa between 2004 and 2009. Multinomial logistic regression analysis was used to explore independent associations between cure-intended treatment modalities and sociodemographic characteristics (age, race/ethnicity, socioeconomic status [SES], and geographic location (rural versus urban)) using patients who did not receive definitive treatment as comparison group. Results: Of 46,971 patients with available treatment data, age-adjusted treatment rates were 39.1% RP, 30.7% RT, and 30.2% for all other non-curative modalities. Compared to patients under 60 years, those ≥60 were less likely to receive RP, patients between 60 and 80 years were more likely to undergo RT, while those 80 years or older were less likely. Non-Hispanic blacks (OR =0.55, 95% CI, 0.50–0.59) and Hispanics (OR = 0.68, 95%CI, 0.62–0.74) were less likely to receive RP compared with whites. Hispanics were significantly less likely to receive RT (OR = 0.78, 95%CI, 0.72–0.85) than blacks and whites. People of low SES were 35% (OR = 0.65, 95%CI, 0.60–0.69) and 15% (OR = 0.85, 95%CI, 0.79–0.90) less likely to receive RP and RT, respectively, compared with those of high SES. Rural-urban status was not associated with cure-intended treatment. Conclusion: Potential sociodemographic disparities exist in the application of cure-intended treatment in localized prostate cancer in Texas particularly in race/ethnicity and SES.

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KW - Prostate cancer

KW - Treatment disparities

KW - Treatment modalities

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