Soft-tissue sarcomas other than rhabdomyosarcoma in children

A. Hayani, D. H. Mahoney, H. K. Hawkins, C. P. Steuber, R. Hurwitz, D. J. Fernbach

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Forty-seven children with nonrhabdomyosarcomatous soft-tissue sarcomas (NRSTS) were treated by the Hematology-Oncology Service at Texas Children's Hospital, Houston, Texas, between 1958 and 1990. The male:female ratio was 1:1, and the median age was 11 years (3 weeks-16 years). A preexisting condition was found in 9/47 (19%) patients including neurofibromatosis (3), Down's syndrome (1), spina bifida (1), congenital facial asymmetry (1), giant pigmented nevus (1), juvenile onset diabetes mellitus (1), and acquired immune deficiency syndrome (1). The site of primary tumor was head and neck (3), trunk (33), and extremities (11). Twenty-four patients (51%) have survived free of disease with a median follow-up of 5 years (4 months-22 years). No patient whose disease recurred achieved a second remission. Of the 19 patients with group I disease, 16 (84%) survived free of disease. Wide excision of the primary tumor, with no microscopic residual disease, was associated with the greatest chance of disease-free survival.

Original languageEnglish (US)
Pages (from-to)114-118
Number of pages5
JournalMedical and Pediatric Oncology
Volume20
Issue number2
DOIs
StatePublished - 1992
Externally publishedYes

Fingerprint

Rhabdomyosarcoma
Sarcoma
Facial Asymmetry
Pigmented Nevus
Preexisting Condition Coverage
Neurofibromatoses
Spinal Dysraphism
Hematology
Down Syndrome
Type 1 Diabetes Mellitus
Disease-Free Survival
Neoplasms
Acquired Immunodeficiency Syndrome
Neck
Extremities
Head

Keywords

  • childhood
  • excision
  • sarcoma
  • soft tissue

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research

Cite this

Hayani, A., Mahoney, D. H., Hawkins, H. K., Steuber, C. P., Hurwitz, R., & Fernbach, D. J. (1992). Soft-tissue sarcomas other than rhabdomyosarcoma in children. Medical and Pediatric Oncology, 20(2), 114-118. https://doi.org/10.1002/mpo.2950200205

Soft-tissue sarcomas other than rhabdomyosarcoma in children. / Hayani, A.; Mahoney, D. H.; Hawkins, H. K.; Steuber, C. P.; Hurwitz, R.; Fernbach, D. J.

In: Medical and Pediatric Oncology, Vol. 20, No. 2, 1992, p. 114-118.

Research output: Contribution to journalArticle

Hayani, A, Mahoney, DH, Hawkins, HK, Steuber, CP, Hurwitz, R & Fernbach, DJ 1992, 'Soft-tissue sarcomas other than rhabdomyosarcoma in children', Medical and Pediatric Oncology, vol. 20, no. 2, pp. 114-118. https://doi.org/10.1002/mpo.2950200205
Hayani A, Mahoney DH, Hawkins HK, Steuber CP, Hurwitz R, Fernbach DJ. Soft-tissue sarcomas other than rhabdomyosarcoma in children. Medical and Pediatric Oncology. 1992;20(2):114-118. https://doi.org/10.1002/mpo.2950200205
Hayani, A. ; Mahoney, D. H. ; Hawkins, H. K. ; Steuber, C. P. ; Hurwitz, R. ; Fernbach, D. J. / Soft-tissue sarcomas other than rhabdomyosarcoma in children. In: Medical and Pediatric Oncology. 1992 ; Vol. 20, No. 2. pp. 114-118.
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