Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice

Keyphrases

• Inhibitor-1 100%
• Bleomycin-induced Pulmonary Fibrosis 100%
• Soluble Epoxide Hydrolase Inhibitor 100%
• 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea 100%
• Bleomycin 87%
• Soluble Epoxide Hydrolase 37%
• Inflammation 25%
• Mouse Model 25%
• Diols 25%
• Transforming Growth Factor-β 25%
• Epoxyeicosatrienoic Acids 25%
• Urea Treatment 25%
• Survival Rate 12%
• Collagen 12%
• Interleukin-1β 12%
• Lung Tissue 12%
• Protective Effect 12%
• Weight Loss 12%
• Collagen Synthesis 12%
• Arachidonic Acid 12%
• α-smooth muscle Actin (α-SMA) 12%
• Mouse Embryonic Fibroblasts 12%
• Anti-inflammatory Properties 12%
• Inflammatory Fibrosis 12%
• Histological Examination 12%
• Collagen Deposition 12%
• IL-6 Level 12%
• Pulmonary Tissue 12%
• Cytochrome P450 Epoxygenases 12%
• Procollagen I 12%
• Pulmonary Fibrosis 12%
• Intratracheal Injection 12%
• Inflammatory Inhibition 12%
• Weight Loss Rate 12%
• Induced Deposition 12%
• Alveolar Structure 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Epoxide Hydrolase 100%
• Bleomycin 100%
• Bleomycin-Induced Pulmonary Fibrosis 100%
• Hydrolase Inhibitor 100%
• Mouse Model 28%
• Inflammation 28%
• Fibrinogen 28%
• Epoxyicosatrienoic Acid 28%
• Cancer Growth Factor 28%
• Cytochrome P450 14%
• Fibrosis 14%
• Anti-Inflammatory Drug 14%
• Survival Rate 14%
• Interleukin 6 14%
• Interleukin 1 14%
• Arachidonic Acid 14%
• Smooth Muscle Actin 14%
• Procollagen 14%
• Lung Fibrosis 14%
• Messenger RNA 14%