Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase

Keyphrases

• C-Met 100%
• Tyrosine Kinase 100%
• Mediated Interaction 100%
• Clathrin-mediated Endocytosis 100%
• Grb2 100%
• Ubiquitin Ligase Activity 28%
• Clathrin 14%
• Endocytosis 14%
• Receptor Internalization 14%
• Phosphotyrosine 14%
• Multisubstrate 14%
• Ubiquitination 7%
• Overexpression 7%
• Adaptor 7%
• Small Interfering RNA (siRNA) 7%
• Ligand-binding Domain 7%
• Dominant Negative 7%
• Lysosomal Degradation 7%
• Receptor Tyrosine Kinase 7%
• Point mutation 7%
• Chimera 7%
• Ubiquitin Ligase 7%
• Ubiquitin 7%
• E3 Ubiquitin Ligase 7%
• Direct Binding 7%
• Conjugation 7%
• Receptor Degradation 7%
• Docking Site 7%
• RNA Depletion 7%
• GAB1 7%

Biochemistry, Genetics and Molecular Biology

• Endocytosis 100%
• Internalization 100%
• Receptor Tyrosine Kinase 100%
• Clathrin 100%
• Tyrosine Kinase 100%
• Ubiquitin Ligase 83%
• Ubiquitination 16%
• Binding Domain 16%
• Ubiquitin 16%
• Point Mutation 16%
• Ubiquitin-Conjugating Enzyme 16%
• Small Interfering RNA 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Clathrin 100%
• Protein Tyrosine Kinase 100%
• Ubiquitin Protein Ligase 100%
• Receptor 80%
• Phosphotyrosine 40%
• Small Interfering RNA 20%
• Ubiquitin 20%
• Ubiquitin Protein Ligase E3 20%