Speckle noise suppression for quantitative analysis of tissue optical properties with OCT

I. Y. Petrova, A. I. Kholodnykh, K. V. Larin, Massoud Motamedi, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2255-2256
Number of pages2
Volume3
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Fingerprint

Optical tomography
Speckle
Optical properties
Tissue
Backscattering
Chemical analysis
Skin
Scattering
Monitoring

Keywords

  • Glucose sensing
  • Laser interferometry
  • Optical coherence tomography
  • Speckles

ASJC Scopus subject areas

  • Bioengineering

Cite this

Petrova, I. Y., Kholodnykh, A. I., Larin, K. V., Motamedi, M., & Esenaliev, R. (2002). Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 2255-2256)

Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. / Petrova, I. Y.; Kholodnykh, A. I.; Larin, K. V.; Motamedi, Massoud; Esenaliev, Rinat.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. p. 2255-2256.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Petrova, IY, Kholodnykh, AI, Larin, KV, Motamedi, M & Esenaliev, R 2002, Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 3, pp. 2255-2256, Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States, 10/23/02.
Petrova IY, Kholodnykh AI, Larin KV, Motamedi M, Esenaliev R. Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3. 2002. p. 2255-2256
Petrova, I. Y. ; Kholodnykh, A. I. ; Larin, K. V. ; Motamedi, Massoud ; Esenaliev, Rinat. / Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. pp. 2255-2256
@inproceedings{dd52f82e1890431297e806a60313598e,
title = "Speckle noise suppression for quantitative analysis of tissue optical properties with OCT",
abstract = "Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65{\%} and may reach 0.1-0.2{\%} if optimum averaging parameters are used.",
keywords = "Glucose sensing, Laser interferometry, Optical coherence tomography, Speckles",
author = "Petrova, {I. Y.} and Kholodnykh, {A. I.} and Larin, {K. V.} and Massoud Motamedi and Rinat Esenaliev",
year = "2002",
language = "English (US)",
volume = "3",
pages = "2255--2256",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

}

TY - GEN

T1 - Speckle noise suppression for quantitative analysis of tissue optical properties with OCT

AU - Petrova, I. Y.

AU - Kholodnykh, A. I.

AU - Larin, K. V.

AU - Motamedi, Massoud

AU - Esenaliev, Rinat

PY - 2002

Y1 - 2002

N2 - Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.

AB - Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.

KW - Glucose sensing

KW - Laser interferometry

KW - Optical coherence tomography

KW - Speckles

UR - http://www.scopus.com/inward/record.url?scp=0036911481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036911481&partnerID=8YFLogxK

M3 - Conference contribution

VL - 3

SP - 2255

EP - 2256

BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ER -