Abstract
Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.
| Original language | English (US) |
|---|---|
| Title of host publication | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Pages | 2255-2256 |
| Number of pages | 2 |
| Volume | 3 |
| State | Published - 2002 |
| Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Other
| Other | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) |
|---|---|
| Country | United States |
| City | Houston, TX |
| Period | 10/23/02 → 10/26/02 |
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Keywords
- Glucose sensing
- Laser interferometry
- Optical coherence tomography
- Speckles
ASJC Scopus subject areas
- Bioengineering
Cite this
Speckle noise suppression for quantitative analysis of tissue optical properties with OCT. / Petrova, I. Y.; Kholodnykh, A. I.; Larin, K. V.; Motamedi, Massoud; Esenaliev, Rinat.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. p. 2255-2256.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Speckle noise suppression for quantitative analysis of tissue optical properties with OCT
AU - Petrova, I. Y.
AU - Kholodnykh, A. I.
AU - Larin, K. V.
AU - Motamedi, Massoud
AU - Esenaliev, Rinat
PY - 2002
Y1 - 2002
N2 - Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.
AB - Measurement of tissue optical properties can be used for noninvasive monitoring of analytes and tissue characterization. Noninvasive measurement of tissue optical properties (attenuation, scattering coefficient, optical thickness, etc.) can be performed with optical coherence tomography (OCT) technique. However, speckle noise substantially deteriorates the accuracy of the measurements with this technique. In this paper, we studied suppression of speckle noise for accurate measurement of backscattering signal with the OCT technique. The backscattering signal variance resulted from speckle noise was experimentally determined for a scattering standard and human skin. The dependence of speckle and electronic noise on the range of spatial and temporal averaging of OCT signals was studied. Our results demonstrated that the accuracy of measurement of backscattering signals with OCT technique from skin can be 0.65% and may reach 0.1-0.2% if optimum averaging parameters are used.
KW - Glucose sensing
KW - Laser interferometry
KW - Optical coherence tomography
KW - Speckles
UR - http://www.scopus.com/inward/record.url?scp=0036911481&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036911481&partnerID=8YFLogxK
M3 - Conference contribution
VL - 3
SP - 2255
EP - 2256
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ER -