Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host

Keyphrases

• Leishmania 100%
• Mammalian Host 100%
• Promastigote 100%
• Leishmania Major 100%
• Acidic pH 100%
• Sphingolipids 100%
• Immunodeficient Mice 66%
• Nitrosative Stress 66%
• Elevated Temperature 66%
• T Cell Response 33%
• Immune Response 33%
• Host Cell 33%
• Leishmania Infection 33%
• Virulence 33%
• Interleukin-12 (IL-12) 33%
• Cell Activation 33%
• Nitric Oxide 33%
• Serious Disease 33%
• Sand Fly 33%
• Infected Mice 33%
• Macrophage Activation 33%
• L. Major 33%
• Phagocytes 33%
• Leishmania Parasites 33%
• Amastigote 33%
• Adverse Conditions 33%
• Murine Macrophages 33%
• Evade 33%
• Acidification 33%
• Acidic Environment 33%
• Harsh Conditions 33%
• Stationary Phase 33%
• Phagolysosome 33%
• Sphingolipid Metabolism 33%

Immunology and Microbiology

• Leishmania 100%
• Leishmania Major 100%
• Promastigote 75%
• Parasitology 75%
• Wild Type 50%
• Nitrosative Stress 50%
• T Cell 25%
• Immune Response 25%
• Host Cell 25%
• Leishmaniasis 25%
• Macrophage 25%
• Macrophage Activation 25%
• Cell Activation 25%
• Phlebotominae 25%
• Phagocyte 25%
• Amastigote 25%
• Murine 25%
• Phagolysosome 25%
• Sphingolipid Metabolism 25%
• Interleukin 12 25%