Spindle cell lesions of the breast: Multimodality imaging and clinical differentiation of pathologically similar neoplasms

Sean D. Raj, Kevin Sweetwood, Megha M. Kapoor, Karuna M. Raj, Chandandeep Nagi, Karla A. Sepulveda, Emily L. Sedgwick

Research output: Contribution to journalReview article

2 Scopus citations


Spindle cell lesions of the breast comprise a wide-range of entities including reactive, benign and malignant proliferations. They can be pathologically challenging to differentiate as there is often immunohistochemical and morphologic similarities with characteristic spindle shaped cellular patterns. Radiological and pathological correlation is essential. Radiology detects, defines the size and extent, and assists in localizing the lesions. Pathology confirms the diagnosis and provides prognostic parameters. Familiarity with the clinicoradiological features of these diagnostically challenging lesions helps to establish an accurate pathological diagnosis and subsequent clinical decision making.

Original languageEnglish (US)
Pages (from-to)60-72
Number of pages13
JournalEuropean Journal of Radiology
StatePublished - May 1 2017



  • Carcinoma
  • Invasive ductal carcinoma subtypes
  • Spindle cell lesions

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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