Splenic toxicology

M. F. Khan

doi:10.1016/B978-0-12-409548-9.11759-2

Splenic toxicology

M. F. Khan

Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Even though spleen carries out several very important biological functions, little efforts have been made in understanding the splenotoxic effects resulting due to exposure to a variety of agents, and in-depth studies providing mechanistic explanation of splenic toxicity are lacking. Clearly, there is a need to understand how environmental agents elicit splenotoxic responses, especially with respect to human exposure to such agents.

Original language	English (US)
Title of host publication	Encyclopedia of Environmental Health
Publisher	Elsevier
Pages	799-804
Number of pages	6
ISBN (Electronic)	9780444639523
ISBN (Print)	9780444639516
DOIs	https://doi.org/10.1016/B978-0-12-409548-9.11759-2
State	Published - Jan 1 2019

Keywords

Aniline
Cell signaling
DNA damage
Environmental agents
Fibrosarcomas
Fibrosis
Iron overload
Lipid peroxidation
Oxidative stress
Protein oxidation
Red blood cells
Spleen

ASJC Scopus subject areas

General Environmental Science

Access to Document

10.1016/B978-0-12-409548-9.11759-2

Cite this

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title = "Splenic toxicology",

abstract = "Even though spleen carries out several very important biological functions, little efforts have been made in understanding the splenotoxic effects resulting due to exposure to a variety of agents, and in-depth studies providing mechanistic explanation of splenic toxicity are lacking. Clearly, there is a need to understand how environmental agents elicit splenotoxic responses, especially with respect to human exposure to such agents.",

keywords = "Aniline, Cell signaling, DNA damage, Environmental agents, Fibrosarcomas, Fibrosis, Iron overload, Lipid peroxidation, Oxidative stress, Protein oxidation, Red blood cells, Spleen",

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AU - Khan, M. F.

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Y1 - 2019/1/1

N2 - Even though spleen carries out several very important biological functions, little efforts have been made in understanding the splenotoxic effects resulting due to exposure to a variety of agents, and in-depth studies providing mechanistic explanation of splenic toxicity are lacking. Clearly, there is a need to understand how environmental agents elicit splenotoxic responses, especially with respect to human exposure to such agents.

AB - Even though spleen carries out several very important biological functions, little efforts have been made in understanding the splenotoxic effects resulting due to exposure to a variety of agents, and in-depth studies providing mechanistic explanation of splenic toxicity are lacking. Clearly, there is a need to understand how environmental agents elicit splenotoxic responses, especially with respect to human exposure to such agents.

KW - Aniline

KW - Cell signaling

KW - DNA damage

KW - Environmental agents

KW - Fibrosarcomas

KW - Fibrosis

KW - Iron overload

KW - Lipid peroxidation

KW - Oxidative stress

KW - Protein oxidation

KW - Red blood cells

KW - Spleen

UR - http://www.scopus.com/inward/record.url?scp=85079533108&partnerID=8YFLogxK

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U2 - 10.1016/B978-0-12-409548-9.11759-2

DO - 10.1016/B978-0-12-409548-9.11759-2

M3 - Chapter

AN - SCOPUS:85079533108

SN - 9780444639516

SP - 799

EP - 804

BT - Encyclopedia of Environmental Health

PB - Elsevier

ER -

Splenic toxicology

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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