Abstract
Even though spleen carries out several very important biological functions, little efforts have been made in understanding the splenotoxic effects resulting due to exposure to a variety of agents, and in-depth studies providing mechanistic explanation of splenic toxicity are lacking. Clearly, there is a need to understand how environmental agents elicit splenotoxic responses, especially with respect to human exposure to such agents.
| Original language | English (US) |
|---|---|
| Title of host publication | Encyclopedia of Environmental Health |
| Publisher | Elsevier |
| Pages | 799-804 |
| Number of pages | 6 |
| ISBN (Electronic) | 9780444639523 |
| ISBN (Print) | 9780444639516 |
| DOIs | |
| State | Published - Jan 1 2019 |
Keywords
- Aniline
- Cell signaling
- DNA damage
- Environmental agents
- Fibrosarcomas
- Fibrosis
- Iron overload
- Lipid peroxidation
- Oxidative stress
- Protein oxidation
- Red blood cells
- Spleen
ASJC Scopus subject areas
- General Environmental Science
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