TY - JOUR
T1 - Squamous cell carcinoma diagnosed as a suspected neuroendocrine tumor by gallium-68 DOTA-Tyr3-octreotate positron emission tomography scan
T2 - A case report
AU - Johnson, Tori
AU - Chan-Sanchez, Shirley
AU - Pham, Tuan
AU - Gomez, Mariangela
N1 - Publisher Copyright:
© The Author(s) 2025. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Gallium-68 DOTA-Tyr3-octreotate positron emission tomography scan is an important radiologic tool for detecting neuroendocrine tumors. It detects neoplasms by capturing the tumor’s increased density of somatostatin receptor expression. However, multiple neoplastic and non-neoplastic entities express somatostatin receptors, which can be misleading for proper diagnosis. Herein, we report a case of squamous cell carcinoma in a 64-year-old male with a medical history of 20-pack-years of smoking in which a neuroendocrine tumor was suspected per positive gallium-68 DOTA-Tyr3-octreotate imaging. He underwent surgical resection and adjuvant radiation with 6-month post-treatment surveillance positron emission tomography/computed tomography imaging pending.
AB - Gallium-68 DOTA-Tyr3-octreotate positron emission tomography scan is an important radiologic tool for detecting neuroendocrine tumors. It detects neoplasms by capturing the tumor’s increased density of somatostatin receptor expression. However, multiple neoplastic and non-neoplastic entities express somatostatin receptors, which can be misleading for proper diagnosis. Herein, we report a case of squamous cell carcinoma in a 64-year-old male with a medical history of 20-pack-years of smoking in which a neuroendocrine tumor was suspected per positive gallium-68 DOTA-Tyr3-octreotate imaging. He underwent surgical resection and adjuvant radiation with 6-month post-treatment surveillance positron emission tomography/computed tomography imaging pending.
KW - Ga-DOTATATE
KW - neuroendocrine tumor (NET)
KW - PET DOTATATE
KW - somatostatin receptor
KW - squamous cell carcinoma (SCC)
UR - https://www.scopus.com/pages/publications/105024568241
UR - https://www.scopus.com/pages/publications/105024568241#tab=citedBy
U2 - 10.1177/2050313X251372003
DO - 10.1177/2050313X251372003
M3 - Article
AN - SCOPUS:105024568241
SN - 2050-313X
VL - 13
JO - SAGE Open Medical Case Reports
JF - SAGE Open Medical Case Reports
ER -