Stability of SARS-CoV-2 and other airborne viruses under different stress conditions

Marcilio Jorge Fumagalli, Carlos Fabiano Capato, Luiza Antunes de Castro-Jorge, William Marciel de Souza, Eurico Arruda, Luiz Tadeu Moraes Figueiredo

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Viral stability under stress conditions may directly affect viral dissemination, seasonality, and pathogenesis. We exposed airborne viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mumps virus, coxsackievirus B5, human rhinovirus A16, and respiratory syncytial virus, to different temperatures, UV light exposure time, pH values, and osmotic pressures and measured the remaining viral infectivity. Reduced thermal stability was observed for coxsackievirus B5 at 45 °C, while SARS-CoV-2 demonstrated residual infectivity at 55 °C. UV light exposure was an efficient means of viral inactivation but was less efficient for non-enveloped viruses. Rhinovirus A16 and respiratory syncytial virus demonstrated extreme sensitivity to acid conditions, while SARS-CoV-2, rhinovirus A16, and respiratory syncytial virus were unstable in an alkaline environment. The information obtained in this study will be useful for the development of viral inactivation methods and may be correlated with epidemiological and seasonal viral characteristics.

Original languageEnglish (US)
Pages (from-to)183-187
Number of pages5
JournalArchives of virology
Issue number1
StatePublished - Jan 2022
Externally publishedYes

ASJC Scopus subject areas

  • Virology


Dive into the research topics of 'Stability of SARS-CoV-2 and other airborne viruses under different stress conditions'. Together they form a unique fingerprint.

Cite this