Status of research and development of vaccines for chikungunya

Claire Smalley; Jesse H. Erasmus; Charles B. Chesson; David W.C. Beasley

doi:10.1016/j.vaccine.2016.03.076

Status of research and development of vaccines for chikungunya

Claire Smalley, Jesse H. Erasmus, Charles B. Chesson, David W.C. Beasley

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Abstract

Chikungunya virus (CHIKV) is an arthritogenic alphavirus that during the last decade has significantly expanded its geographical range and caused large outbreaks of human disease around the world. Although mortality rates associated with CHIKV outbreaks are low, acute and chronic illnesses caused by CHIKV represent a significant burden of disease largely affecting low and middle income countries. This report summarizes the current status of vaccine development for CHIKV.

Original language	English (US)
Pages (from-to)	2976-2981
Number of pages	6
Journal	Vaccine
Volume	34
Issue number	26
DOIs	https://doi.org/10.1016/j.vaccine.2016.03.076
State	Published - Jun 3 2016

Keywords

Alphavirus
Chikungunya
Emerging disease
Polyarthralgia
Vaccine

ASJC Scopus subject areas

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.vaccine.2016.03.076

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title = "Status of research and development of vaccines for chikungunya",

abstract = "Chikungunya virus (CHIKV) is an arthritogenic alphavirus that during the last decade has significantly expanded its geographical range and caused large outbreaks of human disease around the world. Although mortality rates associated with CHIKV outbreaks are low, acute and chronic illnesses caused by CHIKV represent a significant burden of disease largely affecting low and middle income countries. This report summarizes the current status of vaccine development for CHIKV.",

keywords = "Alphavirus, Chikungunya, Emerging disease, Polyarthralgia, Vaccine",

author = "Claire Smalley and Erasmus, {Jesse H.} and Chesson, {Charles B.} and Beasley, {David W.C.}",

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AU - Smalley, Claire

AU - Erasmus, Jesse H.

AU - Chesson, Charles B.

AU - Beasley, David W.C.

PY - 2016/6/3

Y1 - 2016/6/3

N2 - Chikungunya virus (CHIKV) is an arthritogenic alphavirus that during the last decade has significantly expanded its geographical range and caused large outbreaks of human disease around the world. Although mortality rates associated with CHIKV outbreaks are low, acute and chronic illnesses caused by CHIKV represent a significant burden of disease largely affecting low and middle income countries. This report summarizes the current status of vaccine development for CHIKV.

AB - Chikungunya virus (CHIKV) is an arthritogenic alphavirus that during the last decade has significantly expanded its geographical range and caused large outbreaks of human disease around the world. Although mortality rates associated with CHIKV outbreaks are low, acute and chronic illnesses caused by CHIKV represent a significant burden of disease largely affecting low and middle income countries. This report summarizes the current status of vaccine development for CHIKV.

KW - Alphavirus

KW - Chikungunya

KW - Emerging disease

KW - Polyarthralgia

KW - Vaccine

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JF - Vaccine

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ER -

Status of research and development of vaccines for chikungunya

Abstract

Keywords

ASJC Scopus subject areas

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