Strongyloides stercoralis infection at different altitudes of the cusco region in Peru

Maria Luisa Morales, Martha Lopez, Priscilla Ly, Seher Anjum, Martha Vanessa Fernandez-Baca, Angela Maria Valdivia-Rodriguez, Frecia Maribel Mamani-Licona, Benicia Baca-Turpo, Nedhy Farfan-Gonzales, Yeshica Chaman-Illanes, Miguel Cabada

Research output: Contribution to journalArticle

Abstract

Strongyloides stercoralis affects 30-100 million people worldwide. The burden is underestimated because of the paucity of studies, limited geographical areas surveyed, and poor quality of diagnostic tests. This study aimed at determining the epidemiology of strongyloidiasis using sensitive microscopy testing in rural populations living at different altitudes in Cusco, Peru. Data were collected from subjects aged > 3 years living in Quellouno (elevation 2,600 ft) and Limatambo (elevation 8,379 ft) districts. Subjects provided one fresh stool sample and answer a standardized questionnaire. Fresh stool was tested on site using the Baermann's test and agar plate culture. Formalin-preserved stool was tested by rapid sedimentation. Eighty percent (585/715) of eligible subjects consented to participate; after excluding subjects with missing data,65%(462/715) were included. Fifty-five percentage were female; the median age was 33 years (interquartile range 13-52), and 72% had government health insurance. Half had intestinal parasites, and Strongyloides was the most common (24.5%) followed by Giardia (15.5%), Blastocystis (14.9%), and hookworm (11.5%). The agar plate culture detected more cases of Strongyloides than Baermann's or sedimentation tests. Strongyloides infection was more common at low altitude (26.4%) than at high altitude (18.6%), but the difference was not statistically significant (P = 0.08). Older age, walking barefoot, bathing in rivers/streams, and using municipal sewage were associated with strongyloidiasis. Strongyloides was the most prevalent parasite in the areas studied and was associated with demographic, socioeconomic, and sanitary factors.

Original languageEnglish (US)
Pages (from-to)422-427
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume101
Issue number2
DOIs
StatePublished - Jan 1 2019

Fingerprint

Strongyloides
Strongyloides stercoralis
Peru
Strongyloidiasis
Infection
Agar
Parasites
Blastocystis
Ancylostomatoidea
Giardia
Rural Population
Health Insurance
Sewage
Routine Diagnostic Tests
Rivers
Formaldehyde
Walking
Microscopy
Epidemiology
Demography

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Strongyloides stercoralis infection at different altitudes of the cusco region in Peru. / Morales, Maria Luisa; Lopez, Martha; Ly, Priscilla; Anjum, Seher; Fernandez-Baca, Martha Vanessa; Valdivia-Rodriguez, Angela Maria; Mamani-Licona, Frecia Maribel; Baca-Turpo, Benicia; Farfan-Gonzales, Nedhy; Chaman-Illanes, Yeshica; Cabada, Miguel.

In: American Journal of Tropical Medicine and Hygiene, Vol. 101, No. 2, 01.01.2019, p. 422-427.

Research output: Contribution to journalArticle

Morales, ML, Lopez, M, Ly, P, Anjum, S, Fernandez-Baca, MV, Valdivia-Rodriguez, AM, Mamani-Licona, FM, Baca-Turpo, B, Farfan-Gonzales, N, Chaman-Illanes, Y & Cabada, M 2019, 'Strongyloides stercoralis infection at different altitudes of the cusco region in Peru', American Journal of Tropical Medicine and Hygiene, vol. 101, no. 2, pp. 422-427. https://doi.org/10.4269/ajtmh.18-0568
Morales ML, Lopez M, Ly P, Anjum S, Fernandez-Baca MV, Valdivia-Rodriguez AM et al. Strongyloides stercoralis infection at different altitudes of the cusco region in Peru. American Journal of Tropical Medicine and Hygiene. 2019 Jan 1;101(2):422-427. https://doi.org/10.4269/ajtmh.18-0568
Morales, Maria Luisa ; Lopez, Martha ; Ly, Priscilla ; Anjum, Seher ; Fernandez-Baca, Martha Vanessa ; Valdivia-Rodriguez, Angela Maria ; Mamani-Licona, Frecia Maribel ; Baca-Turpo, Benicia ; Farfan-Gonzales, Nedhy ; Chaman-Illanes, Yeshica ; Cabada, Miguel. / Strongyloides stercoralis infection at different altitudes of the cusco region in Peru. In: American Journal of Tropical Medicine and Hygiene. 2019 ; Vol. 101, No. 2. pp. 422-427.
@article{e7d888cbbd7b4bf18ff997e6e131b5b4,
title = "Strongyloides stercoralis infection at different altitudes of the cusco region in Peru",
abstract = "Strongyloides stercoralis affects 30-100 million people worldwide. The burden is underestimated because of the paucity of studies, limited geographical areas surveyed, and poor quality of diagnostic tests. This study aimed at determining the epidemiology of strongyloidiasis using sensitive microscopy testing in rural populations living at different altitudes in Cusco, Peru. Data were collected from subjects aged > 3 years living in Quellouno (elevation 2,600 ft) and Limatambo (elevation 8,379 ft) districts. Subjects provided one fresh stool sample and answer a standardized questionnaire. Fresh stool was tested on site using the Baermann's test and agar plate culture. Formalin-preserved stool was tested by rapid sedimentation. Eighty percent (585/715) of eligible subjects consented to participate; after excluding subjects with missing data,65{\%}(462/715) were included. Fifty-five percentage were female; the median age was 33 years (interquartile range 13-52), and 72{\%} had government health insurance. Half had intestinal parasites, and Strongyloides was the most common (24.5{\%}) followed by Giardia (15.5{\%}), Blastocystis (14.9{\%}), and hookworm (11.5{\%}). The agar plate culture detected more cases of Strongyloides than Baermann's or sedimentation tests. Strongyloides infection was more common at low altitude (26.4{\%}) than at high altitude (18.6{\%}), but the difference was not statistically significant (P = 0.08). Older age, walking barefoot, bathing in rivers/streams, and using municipal sewage were associated with strongyloidiasis. Strongyloides was the most prevalent parasite in the areas studied and was associated with demographic, socioeconomic, and sanitary factors.",
author = "Morales, {Maria Luisa} and Martha Lopez and Priscilla Ly and Seher Anjum and Fernandez-Baca, {Martha Vanessa} and Valdivia-Rodriguez, {Angela Maria} and Mamani-Licona, {Frecia Maribel} and Benicia Baca-Turpo and Nedhy Farfan-Gonzales and Yeshica Chaman-Illanes and Miguel Cabada",
year = "2019",
month = "1",
day = "1",
doi = "10.4269/ajtmh.18-0568",
language = "English (US)",
volume = "101",
pages = "422--427",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

TY - JOUR

T1 - Strongyloides stercoralis infection at different altitudes of the cusco region in Peru

AU - Morales, Maria Luisa

AU - Lopez, Martha

AU - Ly, Priscilla

AU - Anjum, Seher

AU - Fernandez-Baca, Martha Vanessa

AU - Valdivia-Rodriguez, Angela Maria

AU - Mamani-Licona, Frecia Maribel

AU - Baca-Turpo, Benicia

AU - Farfan-Gonzales, Nedhy

AU - Chaman-Illanes, Yeshica

AU - Cabada, Miguel

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Strongyloides stercoralis affects 30-100 million people worldwide. The burden is underestimated because of the paucity of studies, limited geographical areas surveyed, and poor quality of diagnostic tests. This study aimed at determining the epidemiology of strongyloidiasis using sensitive microscopy testing in rural populations living at different altitudes in Cusco, Peru. Data were collected from subjects aged > 3 years living in Quellouno (elevation 2,600 ft) and Limatambo (elevation 8,379 ft) districts. Subjects provided one fresh stool sample and answer a standardized questionnaire. Fresh stool was tested on site using the Baermann's test and agar plate culture. Formalin-preserved stool was tested by rapid sedimentation. Eighty percent (585/715) of eligible subjects consented to participate; after excluding subjects with missing data,65%(462/715) were included. Fifty-five percentage were female; the median age was 33 years (interquartile range 13-52), and 72% had government health insurance. Half had intestinal parasites, and Strongyloides was the most common (24.5%) followed by Giardia (15.5%), Blastocystis (14.9%), and hookworm (11.5%). The agar plate culture detected more cases of Strongyloides than Baermann's or sedimentation tests. Strongyloides infection was more common at low altitude (26.4%) than at high altitude (18.6%), but the difference was not statistically significant (P = 0.08). Older age, walking barefoot, bathing in rivers/streams, and using municipal sewage were associated with strongyloidiasis. Strongyloides was the most prevalent parasite in the areas studied and was associated with demographic, socioeconomic, and sanitary factors.

AB - Strongyloides stercoralis affects 30-100 million people worldwide. The burden is underestimated because of the paucity of studies, limited geographical areas surveyed, and poor quality of diagnostic tests. This study aimed at determining the epidemiology of strongyloidiasis using sensitive microscopy testing in rural populations living at different altitudes in Cusco, Peru. Data were collected from subjects aged > 3 years living in Quellouno (elevation 2,600 ft) and Limatambo (elevation 8,379 ft) districts. Subjects provided one fresh stool sample and answer a standardized questionnaire. Fresh stool was tested on site using the Baermann's test and agar plate culture. Formalin-preserved stool was tested by rapid sedimentation. Eighty percent (585/715) of eligible subjects consented to participate; after excluding subjects with missing data,65%(462/715) were included. Fifty-five percentage were female; the median age was 33 years (interquartile range 13-52), and 72% had government health insurance. Half had intestinal parasites, and Strongyloides was the most common (24.5%) followed by Giardia (15.5%), Blastocystis (14.9%), and hookworm (11.5%). The agar plate culture detected more cases of Strongyloides than Baermann's or sedimentation tests. Strongyloides infection was more common at low altitude (26.4%) than at high altitude (18.6%), but the difference was not statistically significant (P = 0.08). Older age, walking barefoot, bathing in rivers/streams, and using municipal sewage were associated with strongyloidiasis. Strongyloides was the most prevalent parasite in the areas studied and was associated with demographic, socioeconomic, and sanitary factors.

UR - http://www.scopus.com/inward/record.url?scp=85071349097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071349097&partnerID=8YFLogxK

U2 - 10.4269/ajtmh.18-0568

DO - 10.4269/ajtmh.18-0568

M3 - Article

C2 - 31264557

AN - SCOPUS:85071349097

VL - 101

SP - 422

EP - 427

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 2

ER -