Keyphrases
Specific Inhibitor
100%
Methylenetetrahydrofolate Reductase (MTHFR)
100%
Analog Design
100%
Cryptosporidium Hominis
100%
Thymidylate Synthase
100%
Active Sites
28%
Cryptosporidiosis
14%
Cell Culture
14%
Protein Residue
14%
In Cancer
14%
Causative Agents
14%
Malaria
14%
Bacterial Infection
14%
Nicotinamide Adenine Dinucleotide Phosphate (NADPH)
14%
Drug Target
14%
Gastrointestinal Diseases
14%
Pyrimidine
14%
Methotrexate
14%
Hydrogen Bonding Interaction
14%
Cryptosporidium
14%
Enzyme Inhibition
14%
Substrate Analog
14%
Bifunctional
14%
Essential Enzymes
14%
2-amino-4
14%
Human Enzymes
14%
Pyrrol
14%
Monophosphate
14%
Antifolate
14%
Reductase Enzymes
14%
Hydrophobic Bond
14%
Anticryptosporidial
14%
Van Der Waals Bond
14%
Folate Biosynthesis
14%
5-fluorodeoxyuridine
14%
Biosynthesis Pathway
14%
Pharmacology, Toxicology and Pharmaceutical Science
Dihydrofolate Reductase
100%
Cryptosporidium hominis
100%
Thymidylate Synthase
100%
Malignant Neoplasm
14%
Cell Culture
14%
Hydrogen Bond
14%
Gastrointestinal Disease
14%
Bacterial Infection
14%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
14%
Lead Compound
14%
Pyrimidine Derivative
14%
Methotrexate
14%
Enzyme Inhibition
14%
Cryptosporidiosis
14%
Cryptosporidium
14%
Folic Acid
14%
Folic Acid Antagonist
14%
Floxuridine Phosphate
14%