Structure-activity relationship studies on O-alkylamino-tethered salicylamide derivatives with various amino acid linkers as potent anticancer agents

Keyphrases

• Amino Acids 100%
• Structure-activity Relationship Studies 100%
• Linker 100%
• IC50 100%
• Anticancer Agents 100%
• Salicylamide Derivatives 100%
• Apoptosis 50%
• Epithelial Cell Line 50%
• Chemical Structure 50%
• Antiproliferative Activity 50%
• Mechanistic Studies 50%
• Low Toxicity 50%
• SAR Study 50%
• IC50 Value 50%
• Breast Epithelial Cells 50%
• Tumor Growth in Vivo 50%
• MCF10A 50%
• Clinical Development 50%
• Breast Cancer Cell Lines 50%
• MDA-MB-231 Cancer Cells 50%
• MDA-MB-231 50%
• Xenograft Tumor Growth 50%
• STAT3 Phosphorylation 50%
• Triple-negative Breast Cancer 50%
• Triple-negative Breast Cancer Cells 50%
• ER+ Breast Cancer 50%
• MDA-MB-231 Cell Line 50%
• Anticancer Drug Candidates 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Amino Acid 100%
• Structure Activity Relationship 100%
• IC50 100%
• Salicylamide Derivative 100%
• Anticancer Drug 100%
• Triple Negative Breast Cancer 66%
• Tumor Growth 33%
• Breast Cancer 33%
• Anticarcinogen 33%
• Antiproliferative Activity 33%