Keyphrases
Receptor Antagonist
100%
Structure-activity Relationship
100%
P2X7 Receptor (P2X7R)
100%
Activity Optimization
100%
Linker
50%
THP-1 Cells
50%
Antagonistic Activity
50%
Hydrazide
50%
Inducible Nitric Oxide Synthase
25%
Cyclooxygenase-2
25%
Inflammatory Cytokines
25%
Receptor Targets
25%
Chloride
25%
Interleukin-1β
25%
IC50 Value
25%
Inflammatory Pathways
25%
Antagonistic Effect
25%
Anti-inflammatory Agents
25%
Disubstituted
25%
IC50
25%
Acyl
25%
NO Production
25%
Pyridine
25%
HEK293 Cells
25%
Chemical Compounds
25%
Uptake Assay
25%
BzATP
25%
EtBr
25%
Pharmacology, Toxicology and Pharmaceutical Science
Structure Activity Relationship
100%
Receptor Antagonist
100%
IC50
100%
Hydrazide
100%
Receptor
50%
Cytokine
50%
Interleukin 1
50%
Antiinflammatory Agent
50%
Chemistry
Structure-Activity Relationship
100%
IC50
100%
Agent Interacting With Transmitter, Hormone or Drug Receptor
100%
Hydrazide
100%
Anti-Inflammatory Agent
50%
Biochemistry, Genetics and Molecular Biology
Receptor Antagonist
100%
Structure Activity Relation
100%
IC50
100%
Proinflammatory Cytokine
50%
Interleukin-1
50%
Anti-Inflammatory
50%