Structure-based discovery of dengue virus protease inhibitors

Keyphrases

• Dengue Virus 100%
• Dengue Protease 100%
• Protease Inhibitors 100%
• NS2B-NS3 Protease 66%
• Bowman-Birk Inhibitor 66%
• Drug Design 33%
• Viral Replication 33%
• Vaccine Development 33%
• Virus Replication 33%
• Active Sites 33%
• Further Development 33%
• Antiviral Drugs 33%
• Antiretroviral Therapy 33%
• Vaccine Therapy 33%
• Cell Culture Experiment 33%
• Protease Assay 33%
• Protease 33%
• Flaviviridae 33%
• Molecular Modeling 33%
• Protease Domain 33%
• Catalytic Site 33%
• Emerging Pathogen 33%
• Small Molecule Libraries 33%
• Viral Protease 33%
• Polyprotein Processing 33%
• Proteasome Inhibition 33%
• In Vitro Inhibition 33%
• In Vitro Assessment 33%
• Mutational Effects 33%
• Processing Design 33%
• Apo Structure 33%
• Docking Program 33%

Biochemistry, Genetics and Molecular Biology

• Dengue Virus 100%
• Protease Inhibitor 100%
• Protease 100%
• Virus Replication 40%
• Crystal Structure 40%
• Infectious Agent 20%
• Cell Culture 20%
• Active Site 20%
• Flaviviridae 20%
• Molecular Model 20%
• Molecular Library 20%
• Dengue Virus 2 20%
• Proteinase Inhibition 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Proteinase 100%
• Dengue Virus 100%
• Proteinase Inhibitor 100%
• Bowman Birk Inhibitor 33%
• Infectious Agent 16%
• Cell Culture 16%
• Drug Development 16%
• Antiviral Drug 16%
• Antiviral Therapy 16%
• Polyprotein 16%
• Flaviviridae 16%
• Dengue Virus 2 16%