Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation

Keyphrases

• 2-oxoglutarate 33%
• Active Sites 33%
• Allosteric Inhibition 33%
• Allosteric Inhibitor 66%
• Allosteric Regulation 33%
• Binding Site 33%
• Coenzyme Binding 33%
• Complex Patterns 33%
• Complex Phosphates 33%
• Complex Structure 33%
• Dehydrogenase Complex 100%
• Glutamate Dehydrogenase 100%
• Helix 100%
• Hyperammonemia 33%
• Hyperinsulinism 33%
• Kinetic Analysis 33%
• L-glutamine 33%
• NAD+ Binding 33%
• Nicotinamide Adenine Dinucleotide (NAD+) 100%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 33%
• Oxidative Deamination 33%
• Phosphate 33%
• Polyanion 33%
• Purine 100%
• Small Molecules 33%
• Structural Stabilization 33%

Biochemistry, Genetics and Molecular Biology

• Active Site 14%
• Adenosine Diphosphate 42%
• Adenosine Triphosphate 14%
• Allosteric Regulation 14%
• Binding Domain 14%
• Binding Site 14%
• Coenzyme 57%
• Glutamate Dehydrogenase 100%
• Guanosine Triphosphate 100%
• Kinetics 14%
• Nicotinamide Adenine Dinucleotide Phosphate 14%
• Oxidative Deamination 14%
• Small Molecule 14%