Studies on cyclic α-aminoalkanephosphonate compounds: A novel synthesis of 2-phenyl-1,4,2-benzoxaza (or diaza)phosphorin 2-oxides

Jia Zhou, Yongge Qiu, Kesheng Feng, Ruyu Chen

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Numerous cyclic α-aminoalkanephosphonates, 2-phenyl-1,4,2-benzoxaza (or diaza) phosphorin 2-oxides 6a-o and 8 have been prepared by a Mannich-type reaction of o-aminophenol or o-phenylenediamine with phenyldichlorophosphine and aldehydes or ketones. The cis and trans-geometric isomers of the title compounds were stereoselectively generated, depending upon the aldehyde or ketone substrates used. The synthetic methods provide an easy access to the organophosphorus heterocycles with the ring system mentioned above.

Original languageEnglish (US)
Pages (from-to)40-42
Number of pages3
JournalSynthesis
Issue number1
StatePublished - 1999
Externally publishedYes

Fingerprint

Ketones
Aldehydes
Oxides
Isomers
Substrates
phosphate-binding proteolipid
1,2-diaminobenzene
2-aminophenol

Keywords

  • 1,4,2- benzoxaza (or diaza) phosphorin 2-oxides
  • Cyclic α-aminoalkanephosphonates
  • Mannich-type reaction
  • Organophosphorus heterocycles
  • Stereoselectivity

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Studies on cyclic α-aminoalkanephosphonate compounds : A novel synthesis of 2-phenyl-1,4,2-benzoxaza (or diaza)phosphorin 2-oxides. / Zhou, Jia; Qiu, Yongge; Feng, Kesheng; Chen, Ruyu.

In: Synthesis, No. 1, 1999, p. 40-42.

Research output: Contribution to journalArticle

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