Studies on the antigenic relationship among phleboviruses

R. B. Tesh, C. J. Peters, J. M. Meegan

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The antigenic relationship of the 31 currently recognized phlebotomus fever group viruses was examined by plaque reduction neutralization test. Although some low-level cross-neutralization was observed, each of the viruses was easily differentiated by this method. Rift Valley fever virus was shown to be antigenically related to Candiru, Frijoles, Karimabad and Punta Toro viruses. Naples, Tehran and Toscana viruses were also shown to be closely related. Preliminary results of indirect fluorescent antibody tests indicate that this technique is broadly reacting and less specific than either the complement-fixation or neutralization test for identifying phlebotomus fever group viruses. A discussion follows on some of the difficulties encountered in attempting to classify phleboviruses.

Original languageEnglish (US)
Pages (from-to)149-155
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume31
Issue number1
StatePublished - 1982
Externally publishedYes

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Phlebovirus
Sandfly fever Naples virus
Phlebotomus Fever
Viruses
Neutralization Tests
Rift Valley fever virus
Complement Fixation Tests
Antibodies

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Tesh, R. B., Peters, C. J., & Meegan, J. M. (1982). Studies on the antigenic relationship among phleboviruses. American Journal of Tropical Medicine and Hygiene, 31(1), 149-155.

Studies on the antigenic relationship among phleboviruses. / Tesh, R. B.; Peters, C. J.; Meegan, J. M.

In: American Journal of Tropical Medicine and Hygiene, Vol. 31, No. 1, 1982, p. 149-155.

Research output: Contribution to journalArticle

Tesh, RB, Peters, CJ & Meegan, JM 1982, 'Studies on the antigenic relationship among phleboviruses', American Journal of Tropical Medicine and Hygiene, vol. 31, no. 1, pp. 149-155.
Tesh, R. B. ; Peters, C. J. ; Meegan, J. M. / Studies on the antigenic relationship among phleboviruses. In: American Journal of Tropical Medicine and Hygiene. 1982 ; Vol. 31, No. 1. pp. 149-155.
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