Studies on the distribution of lipids within fibrous plaques

L. Clarke Stout

doi:10.1016/0021-9150(76)90006-X

Studies on the distribution of lipids within fibrous plaques

L. Clarke Stout

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The present report is an attempt to determine the nature of the circulation of lipids within fibrous plaques by studying the pattern of lipid distribution within the plaques. The material was obtained from aortas from 405 mammals and birds dying in the Oklahoma City Zoo. Analysis of the pattern of lipid distribution in 187 lipid containing aortic fibrous plaques suggested that most of the lipids entered the plaques at the shoulders and circulated from there toward the centers, usually in the outermost layers of the plaques.

Original language	English (US)
Pages (from-to)	443-450
Number of pages	8
Journal	Atherosclerosis
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/0021-9150(76)90006-X
State	Published - 1976
Externally published	Yes

Keywords

Aorta
Atherosclerosis
Central plaque necrosis
Cholesterol
Endothelial injury
Fatty streaks
Fibrous plaques
Gelatinous lesions
Hemodynamic stress
Lipid insulation
Lipoproteins

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/0021-9150(76)90006-X

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title = "Studies on the distribution of lipids within fibrous plaques",

abstract = "The present report is an attempt to determine the nature of the circulation of lipids within fibrous plaques by studying the pattern of lipid distribution within the plaques. The material was obtained from aortas from 405 mammals and birds dying in the Oklahoma City Zoo. Analysis of the pattern of lipid distribution in 187 lipid containing aortic fibrous plaques suggested that most of the lipids entered the plaques at the shoulders and circulated from there toward the centers, usually in the outermost layers of the plaques.",

keywords = "Aorta, Atherosclerosis, Central plaque necrosis, Cholesterol, Endothelial injury, Fatty streaks, Fibrous plaques, Gelatinous lesions, Hemodynamic stress, Lipid insulation, Lipoproteins",

author = "{Clarke Stout}, L.",

note = "Funding Information: Supported in part by Grants HE 08725 United States Public Health Service.",

year = "1976",

doi = "10.1016/0021-9150(76)90006-X",

language = "English (US)",

volume = "23",

pages = "443--450",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

number = "3",

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PY - 1976

Y1 - 1976

N2 - The present report is an attempt to determine the nature of the circulation of lipids within fibrous plaques by studying the pattern of lipid distribution within the plaques. The material was obtained from aortas from 405 mammals and birds dying in the Oklahoma City Zoo. Analysis of the pattern of lipid distribution in 187 lipid containing aortic fibrous plaques suggested that most of the lipids entered the plaques at the shoulders and circulated from there toward the centers, usually in the outermost layers of the plaques.

AB - The present report is an attempt to determine the nature of the circulation of lipids within fibrous plaques by studying the pattern of lipid distribution within the plaques. The material was obtained from aortas from 405 mammals and birds dying in the Oklahoma City Zoo. Analysis of the pattern of lipid distribution in 187 lipid containing aortic fibrous plaques suggested that most of the lipids entered the plaques at the shoulders and circulated from there toward the centers, usually in the outermost layers of the plaques.

KW - Aorta

KW - Atherosclerosis

KW - Central plaque necrosis

KW - Cholesterol

KW - Endothelial injury

KW - Fatty streaks

KW - Fibrous plaques

KW - Gelatinous lesions

KW - Hemodynamic stress

KW - Lipid insulation

KW - Lipoproteins

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DO - 10.1016/0021-9150(76)90006-X

M3 - Article

C2 - 1267862

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SN - 0021-9150

VL - 23

SP - 443

EP - 450

JO - Atherosclerosis

JF - Atherosclerosis

IS - 3

ER -

Studies on the distribution of lipids within fibrous plaques

Abstract

Keywords

ASJC Scopus subject areas

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