Studies on the distribution of lipids within fibrous plaques

L. Clarke Stout

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The present report is an attempt to determine the nature of the circulation of lipids within fibrous plaques by studying the pattern of lipid distribution within the plaques. The material was obtained from aortas from 405 mammals and birds dying in the Oklahoma City Zoo. Analysis of the pattern of lipid distribution in 187 lipid containing aortic fibrous plaques suggested that most of the lipids entered the plaques at the shoulders and circulated from there toward the centers, usually in the outermost layers of the plaques.

Original languageEnglish (US)
Pages (from-to)443-450
Number of pages8
JournalAtherosclerosis
Volume23
Issue number3
DOIs
StatePublished - Jan 1 1976

Keywords

  • Aorta
  • Atherosclerosis
  • Central plaque necrosis
  • Cholesterol
  • Endothelial injury
  • Fatty streaks
  • Fibrous plaques
  • Gelatinous lesions
  • Hemodynamic stress
  • Lipid insulation
  • Lipoproteins

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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