Successful kidney transplantation in a small child with end-stage renal disease due to angiotensin receptor blocker fetopathy and atretic inferior vena cava

John A. Geha, Joseph D. Geha, Matthew Goss, Michael Kueht, Ronald T. Cotton, Abbas Rana, John A. Goss, Kirti Bhakta, Sarah J. Swartz, Christine A. O'Mahony, Eileen D. Brewer, Nhu T.N. Galvan

Research output: Contribution to journalArticle

Abstract

Kidney transplantation is the treatment of choice in pediatric patients with end-stage renal disease. This population presents technical challenges particularly in those less than 20 kg due to anomalous anatomy, vascular access issues prior to transplantation, and a generally small size for age. Standard allograft outflow is usually achieved utilizing the iliac veins or IVC. When use of the iliocaval system is not feasible, alternative anastomosis must be considered. Herein, we report a case of a pediatric kidney transplantation where successful allograft outflow was achieved using the SMV when he was found to have an atretic IVC intraoperatively. In this setting, use of the portal system was required to achieve adequate allograft outflow. We created a donor iliac graft for added length to anastomose the renal vein with the SMV. In the setting of IVC occlusion with poor drainage, we utilized a patent vessel with larger caliber for outflow to reduce the risk of high venous pressures, allograft failure, venous rotation, and thrombosis. We conclude that the SMV may serve as an alternative outflow tract in the small pediatric patient and provides the vessel caliber needed to reduce the risks of complications.

Original languageEnglish (US)
Article numbere13497
JournalPediatric Transplantation
Volume23
Issue number6
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

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Angiotensin Receptor Antagonists
Inferior Vena Cava
Kidney Transplantation
Chronic Kidney Failure
Allografts
Pediatrics
Iliac Vein
Portal System
Renal Veins
Venous Pressure
Venous Thrombosis
Blood Vessels
Drainage
Anatomy
Transplantation
Tissue Donors
Transplants
Population
Therapeutics

Keywords

  • inferior vena cava
  • kidney transplantation
  • pediatric
  • superior mesenteric vein
  • surgical technique
  • thrombosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

Cite this

Successful kidney transplantation in a small child with end-stage renal disease due to angiotensin receptor blocker fetopathy and atretic inferior vena cava. / Geha, John A.; Geha, Joseph D.; Goss, Matthew; Kueht, Michael; Cotton, Ronald T.; Rana, Abbas; Goss, John A.; Bhakta, Kirti; Swartz, Sarah J.; O'Mahony, Christine A.; Brewer, Eileen D.; Galvan, Nhu T.N.

In: Pediatric Transplantation, Vol. 23, No. 6, e13497, 01.01.2019.

Research output: Contribution to journalArticle

Geha, JA, Geha, JD, Goss, M, Kueht, M, Cotton, RT, Rana, A, Goss, JA, Bhakta, K, Swartz, SJ, O'Mahony, CA, Brewer, ED & Galvan, NTN 2019, 'Successful kidney transplantation in a small child with end-stage renal disease due to angiotensin receptor blocker fetopathy and atretic inferior vena cava', Pediatric Transplantation, vol. 23, no. 6, e13497. https://doi.org/10.1111/petr.13497
Geha, John A. ; Geha, Joseph D. ; Goss, Matthew ; Kueht, Michael ; Cotton, Ronald T. ; Rana, Abbas ; Goss, John A. ; Bhakta, Kirti ; Swartz, Sarah J. ; O'Mahony, Christine A. ; Brewer, Eileen D. ; Galvan, Nhu T.N. / Successful kidney transplantation in a small child with end-stage renal disease due to angiotensin receptor blocker fetopathy and atretic inferior vena cava. In: Pediatric Transplantation. 2019 ; Vol. 23, No. 6.
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