111In chloride bone marrow scintigraphy and ferrokinetic studies in a case of sickle cell anemia with transient erythroid aplasia

Richard E. Helmer, Bettye A. Sayle, Jack B. Alperin, Frank H. Gardner

Research output: Contribution to journalArticle

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Abstract

A patient with sickle cell anemia was hospitalized because of an acute erythropoietic aplastic crisis.111In chloride bone marrow scintigraphy performed during the aplastic crisis showed markedly impaired uptake of the radionuclide and simultaneous r,59Fe clearance T1/2 studies were prolonged (420.9 min). Following recovery from the aplastic crisis111In scintigraphy revealed an expanded marrow and the radioiron clearance T1/2, was accelerated (20.9 min). The clinical course, hemograms and bone marrow aspirations correlated with marrow scintigraphy.111In appears to be a valuable bone marrow scanning agent for assessing the presence of intramedulllary erythropoietic activity.

Original languageEnglish (US)
Pages (from-to)330-333
Number of pages4
JournalActa Haematologica
Volume61
Issue number6
DOIs
StatePublished - Jan 1 1979

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Keywords

  • Erythropoietic aplastic crisis
  • Indium chloride scintigraphy
  • Sickle cell anemia

ASJC Scopus subject areas

  • Hematology

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