111In chloride bone marrow scintigraphy and ferrokinetic studies in a case of sickle cell anemia with transient erythroid aplasia

R. E. Helmer, B. A. Sayle, J. B. Alperin, F. H. Gardner

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2 Citations (Scopus)

Abstract

A patient with sickle cell anemia was hospitalized because of an acute erythropoietic aplastic crisis. 111In chloride bone marrow scintigraphy performed during the aplastic crisis showed markedly impaired uptake of the radionuclide and simultaneous 59Fe clearance T( 1/2 ) studies were prolonged (420.9 min). Following recovery from the aplastic crisis 111In scintigraphy revealed an expanded marrow and the radioiron clearance T( 1/2 ) was accelerated (20.9 min). The clinical course, hemograms and bone marrow aspirations correlated with marrow scintigraphy. 111In appears to be a valuable bone marrow scanning agent for assessing the presence of intramedullary erythropoietic activity.

Original languageEnglish (US)
Pages (from-to)330-333
Number of pages4
JournalActa Haematologica
Volume61
Issue number6
StatePublished - 1979

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Sickle Cell Anemia
Radionuclide Imaging
Chlorides
Bone Marrow
Radioisotopes

ASJC Scopus subject areas

  • Hematology

Cite this

111In chloride bone marrow scintigraphy and ferrokinetic studies in a case of sickle cell anemia with transient erythroid aplasia. / Helmer, R. E.; Sayle, B. A.; Alperin, J. B.; Gardner, F. H.

In: Acta Haematologica, Vol. 61, No. 6, 1979, p. 330-333.

Research output: Contribution to journalArticle

Helmer, R. E. ; Sayle, B. A. ; Alperin, J. B. ; Gardner, F. H. / 111In chloride bone marrow scintigraphy and ferrokinetic studies in a case of sickle cell anemia with transient erythroid aplasia. In: Acta Haematologica. 1979 ; Vol. 61, No. 6. pp. 330-333.
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