Suture type and ultrasound-indicated cerclage efficacy

Vincenzo Berghella, Jeff M. Szychowski, John Owen, Gary Hankins, Jay D. Iams, Jeanne S. Sheffield, Annette Perez-Delboy, Deborah A. Wing, Edwin R. Guzman

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Objective: To assess whether type of suture material affects cerclage efficacy for preterm birth (PTB) prevention. Methods: Secondary analysis of a multicenter trial of ultrasound-indicated cerclage for short cervical length (CL), in which women with prior spontaneous PTB at 1633 6/7 weeks, a singleton gestation and CL < 25 mm between 1622 6/7 weeks, were randomized to McDonald cerclage or no cerclage. Outcomes of women who underwent cerclage were analyzed by type of suture material, comparing polyester braided thread (Mersilene™ or Ethibond™) to Mersilene tape™. Primary outcome was PTB < 35 weeks. Results: 138 women underwent McDonald cerclage: 84 (61%) received polyester braided thread and 46 (33%) Mersilene tape™. Eight (6%) received monofilament suture and were excluded from analysis. Rates of PTB < 35 weeks were similar, 35% for polyester braided thread vs 24% for Mersilene tape™ (p = .24). Birth gestational age was also similar among the 2 groups (p = .18). Conclusion: Type of suture material may not affect ultrasound-indicated cerclage efficacy in high-risk women with short CL, but further study is needed. Polyester braided thread (Mersilene™ or Ethibond™) and polyester braided Mersilene tape™ seem to have similar efficacy.

Original languageEnglish (US)
Pages (from-to)2287-2290
Number of pages4
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume25
Issue number11
DOIs
StatePublished - Nov 2012

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Keywords

  • Cerclage suture
  • Preterm birth prevention
  • Short cervical length

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Berghella, V., Szychowski, J. M., Owen, J., Hankins, G., Iams, J. D., Sheffield, J. S., Perez-Delboy, A., Wing, D. A., & Guzman, E. R. (2012). Suture type and ultrasound-indicated cerclage efficacy. Journal of Maternal-Fetal and Neonatal Medicine, 25(11), 2287-2290. https://doi.org/10.3109/14767058.2012.688081