Abstract
Objective: To assess whether type of suture material affects cerclage efficacy for preterm birth (PTB) prevention. Methods: Secondary analysis of a multicenter trial of ultrasound-indicated cerclage for short cervical length (CL), in which women with prior spontaneous PTB at 1633 6/7 weeks, a singleton gestation and CL < 25 mm between 1622 6/7 weeks, were randomized to McDonald cerclage or no cerclage. Outcomes of women who underwent cerclage were analyzed by type of suture material, comparing polyester braided thread (Mersilene™ or Ethibond™) to Mersilene tape™. Primary outcome was PTB < 35 weeks. Results: 138 women underwent McDonald cerclage: 84 (61%) received polyester braided thread and 46 (33%) Mersilene tape™. Eight (6%) received monofilament suture and were excluded from analysis. Rates of PTB < 35 weeks were similar, 35% for polyester braided thread vs 24% for Mersilene tape™ (p = .24). Birth gestational age was also similar among the 2 groups (p = .18). Conclusion: Type of suture material may not affect ultrasound-indicated cerclage efficacy in high-risk women with short CL, but further study is needed. Polyester braided thread (Mersilene™ or Ethibond™) and polyester braided Mersilene tape™ seem to have similar efficacy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2287-2290 |
| Number of pages | 4 |
| Journal | Journal of Maternal-Fetal and Neonatal Medicine |
| Volume | 25 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2012 |
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Keywords
- Cerclage suture
- Preterm birth prevention
- Short cervical length
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology
Cite this
Suture type and ultrasound-indicated cerclage efficacy. / Berghella, Vincenzo; Szychowski, Jeff M.; Owen, John; Hankins, Gary; Iams, Jay D.; Sheffield, Jeanne S.; Perez-Delboy, Annette; Wing, Deborah A.; Guzman, Edwin R.
In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 25, No. 11, 11.2012, p. 2287-2290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Suture type and ultrasound-indicated cerclage efficacy
AU - Berghella, Vincenzo
AU - Szychowski, Jeff M.
AU - Owen, John
AU - Hankins, Gary
AU - Iams, Jay D.
AU - Sheffield, Jeanne S.
AU - Perez-Delboy, Annette
AU - Wing, Deborah A.
AU - Guzman, Edwin R.
PY - 2012/11
Y1 - 2012/11
N2 - Objective: To assess whether type of suture material affects cerclage efficacy for preterm birth (PTB) prevention. Methods: Secondary analysis of a multicenter trial of ultrasound-indicated cerclage for short cervical length (CL), in which women with prior spontaneous PTB at 1633 6/7 weeks, a singleton gestation and CL < 25 mm between 1622 6/7 weeks, were randomized to McDonald cerclage or no cerclage. Outcomes of women who underwent cerclage were analyzed by type of suture material, comparing polyester braided thread (Mersilene™ or Ethibond™) to Mersilene tape™. Primary outcome was PTB < 35 weeks. Results: 138 women underwent McDonald cerclage: 84 (61%) received polyester braided thread and 46 (33%) Mersilene tape™. Eight (6%) received monofilament suture and were excluded from analysis. Rates of PTB < 35 weeks were similar, 35% for polyester braided thread vs 24% for Mersilene tape™ (p = .24). Birth gestational age was also similar among the 2 groups (p = .18). Conclusion: Type of suture material may not affect ultrasound-indicated cerclage efficacy in high-risk women with short CL, but further study is needed. Polyester braided thread (Mersilene™ or Ethibond™) and polyester braided Mersilene tape™ seem to have similar efficacy.
AB - Objective: To assess whether type of suture material affects cerclage efficacy for preterm birth (PTB) prevention. Methods: Secondary analysis of a multicenter trial of ultrasound-indicated cerclage for short cervical length (CL), in which women with prior spontaneous PTB at 1633 6/7 weeks, a singleton gestation and CL < 25 mm between 1622 6/7 weeks, were randomized to McDonald cerclage or no cerclage. Outcomes of women who underwent cerclage were analyzed by type of suture material, comparing polyester braided thread (Mersilene™ or Ethibond™) to Mersilene tape™. Primary outcome was PTB < 35 weeks. Results: 138 women underwent McDonald cerclage: 84 (61%) received polyester braided thread and 46 (33%) Mersilene tape™. Eight (6%) received monofilament suture and were excluded from analysis. Rates of PTB < 35 weeks were similar, 35% for polyester braided thread vs 24% for Mersilene tape™ (p = .24). Birth gestational age was also similar among the 2 groups (p = .18). Conclusion: Type of suture material may not affect ultrasound-indicated cerclage efficacy in high-risk women with short CL, but further study is needed. Polyester braided thread (Mersilene™ or Ethibond™) and polyester braided Mersilene tape™ seem to have similar efficacy.
KW - Cerclage suture
KW - Preterm birth prevention
KW - Short cervical length
UR - http://www.scopus.com/inward/record.url?scp=84867570612&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867570612&partnerID=8YFLogxK
U2 - 10.3109/14767058.2012.688081
DO - 10.3109/14767058.2012.688081
M3 - Article
VL - 25
SP - 2287
EP - 2290
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - 11
ER -