Synthetic Bone Grafting in Foot and Ankle Surgery

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Synthetic bone graft materials have an established role as osteoconductive materials. The basic function is providing a matrix to support the attachment of bone-forming cells for subsequent bone formation, but these materials in various forms can be used for other functions. They can be used as a vehicle for local antibiotic delivery and in injectable form they can be used in a minimally invasive fashion to fill voids and strengthen purchase of screws in osteoporotic bones. They can provide prolonged structural support, which is important for early weight bearing in the lower extremity. These are some of the qualities that may not be obtained from autograft bone, the traditional gold standard for bone grafting. Therefore, these synthetic bone graft substitutes have earned a unique place in the armamentarium when issues such as bone defect, bone quality, and bone infection challenge bone healing and repair. This article reviews the basic science and use of such materials in foot and ankle surgery for conditions related to trauma, tumors, and infection.

Original languageEnglish (US)
Pages (from-to)559-576
Number of pages18
JournalFoot and Ankle Clinics
Volume15
Issue number4
DOIs
StatePublished - Dec 2010

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Bone Transplantation
Ankle
Foot
Bone and Bones
Transplants
Bone Substitutes
Autografts
Weight-Bearing
Infection
Osteogenesis
Lower Extremity
Anti-Bacterial Agents
Injections
Wounds and Injuries
Neoplasms

Keywords

  • Calcium phosphate
  • Calcium sulfate
  • Synthetic bone graft

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Synthetic Bone Grafting in Foot and Ankle Surgery. / Panchbhavi, Vinod.

In: Foot and Ankle Clinics, Vol. 15, No. 4, 12.2010, p. 559-576.

Research output: Contribution to journalArticle

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