Syrian Golden Hamster Model for Nipah Virus Infection

Terry Juelich, Jennifer Smith, Alexander N. Freiberg

Research output: Chapter in Book/Report/Conference proceedingChapter


Small rodent animal models that recapitulate the symptomology and pathology of the human disease caused by Nipah virus (NiV) are crucial not only to study virus-induced disease but also a critical component for the development of vaccine and therapeutic candidates. The Syrian golden hamster is the most commonly used small animal model for NiV and develops clinical symptoms and pathologies that closely resemble NiV disease in humans. In this chapter, we describe standard techniques used to infect hamsters and conduct evaluation of therapeutics and vaccine candidates.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages11
StatePublished - 2023

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029


  • Antiviral
  • Nipah virus
  • Pathogenicity
  • Small animal model
  • Syrian golden hamster
  • Vaccine

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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