Tamiami virus infection in mice and cotton rats

W. C. Winn, F. A. Murphy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Tamiami virus produces a lethal encephalitis in suckling mice, and the illness is mediated, at least in part, by cellular immunity. Infection of extraneural organs, including lymphoid organs, is limited. The same virus produces a widespread infection in its natural hosts, the cotton rat, but neither symptomatic illness nor cytopathology results. Since antibody is produced, as in the murine infection, suppression of cellular immunity to the virus may be responsible for the non cytolytic infection. Lymphoid tissue is extensively infected in the cotton rat and a relation between this lymphotropism and immunosuppression is suggested.

Original languageEnglish (US)
Pages (from-to)501-506
Number of pages6
JournalBulletin of the World Health Organization
Volume52
Issue number4-5 6
StatePublished - 1975

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Sigmodontinae
Virus Diseases
Viruses
Infection
Cellular Immunity
Lymphoid Tissue
Encephalitis
Immunosuppression
Antibodies

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Winn, W. C., & Murphy, F. A. (1975). Tamiami virus infection in mice and cotton rats. Bulletin of the World Health Organization, 52(4-5 6), 501-506.

Tamiami virus infection in mice and cotton rats. / Winn, W. C.; Murphy, F. A.

In: Bulletin of the World Health Organization, Vol. 52, No. 4-5 6, 1975, p. 501-506.

Research output: Contribution to journalArticle

Winn, WC & Murphy, FA 1975, 'Tamiami virus infection in mice and cotton rats', Bulletin of the World Health Organization, vol. 52, no. 4-5 6, pp. 501-506.
Winn, W. C. ; Murphy, F. A. / Tamiami virus infection in mice and cotton rats. In: Bulletin of the World Health Organization. 1975 ; Vol. 52, No. 4-5 6. pp. 501-506.
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