Tamiami virus infection in mice and cotton rats

W. C. Winn, F. A. Murphy

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Tamiami virus produces a lethal encephalitis in suckling mice, and the illness is mediated, at least in part, by cellular immunity. Infection of extraneural organs, including lymphoid organs, is limited. The same virus produces a widespread infection in its natural hosts, the cotton rat, but neither symptomatic illness nor cytopathology results. Since antibody is produced, as in the murine infection, suppression of cellular immunity to the virus may be responsible for the non cytolytic infection. Lymphoid tissue is extensively infected in the cotton rat and a relation between this lymphotropism and immunosuppression is suggested.

Original languageEnglish (US)
Pages (from-to)501-506
Number of pages6
JournalBulletin of the World Health Organization
Issue number4-5 6
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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