Target highlights in CASP13: Experimental target structures through the eyes of their authors

Rosalba Lepore, Andriy Kryshtafovych, Markus Alahuhta, Harshul A. Veraszto, Yannick J. Bomble, Joshua C. Bufton, Alex N. Bullock, Cody Caba, Hongnan Cao, Owen R. Davies, Ambroise Desfosses, Matthew Dunne, Krzysztof Fidelis, Celia W. Goulding, Manickam Gurusaran, Irina Gutsche, Christopher J. Harding, Marcus D. Hartmann, Christopher S. Hayes, Andrzej JoachimiakPetr G. Leiman, Peter Loppnau, Andrew L. Lovering, Vladimir V. Lunin, Karolina Michalska, Ignacio Mir-Sanchis, A. K. Mitra, John Moult, George N. Phillips, Daniel M. Pinkas, Phoebe A. Rice, Yufeng Tong, Maya Topf, Jonathan D. Walton, Torsten Schwede

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

Original languageEnglish (US)
Pages (from-to)1037-1057
Number of pages21
JournalProteins: Structure, Function and Bioinformatics
Volume87
Issue number12
DOIs
StatePublished - Dec 1 2019

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Proteins
Experiments

Keywords

  • CASP, protein structure prediction
  • cryo-EM
  • X-ray crystallography

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Molecular Biology

Cite this

Lepore, R., Kryshtafovych, A., Alahuhta, M., Veraszto, H. A., Bomble, Y. J., Bufton, J. C., ... Schwede, T. (2019). Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins: Structure, Function and Bioinformatics, 87(12), 1037-1057. https://doi.org/10.1002/prot.25805

Target highlights in CASP13 : Experimental target structures through the eyes of their authors. / Lepore, Rosalba; Kryshtafovych, Andriy; Alahuhta, Markus; Veraszto, Harshul A.; Bomble, Yannick J.; Bufton, Joshua C.; Bullock, Alex N.; Caba, Cody; Cao, Hongnan; Davies, Owen R.; Desfosses, Ambroise; Dunne, Matthew; Fidelis, Krzysztof; Goulding, Celia W.; Gurusaran, Manickam; Gutsche, Irina; Harding, Christopher J.; Hartmann, Marcus D.; Hayes, Christopher S.; Joachimiak, Andrzej; Leiman, Petr G.; Loppnau, Peter; Lovering, Andrew L.; Lunin, Vladimir V.; Michalska, Karolina; Mir-Sanchis, Ignacio; Mitra, A. K.; Moult, John; Phillips, George N.; Pinkas, Daniel M.; Rice, Phoebe A.; Tong, Yufeng; Topf, Maya; Walton, Jonathan D.; Schwede, Torsten.

In: Proteins: Structure, Function and Bioinformatics, Vol. 87, No. 12, 01.12.2019, p. 1037-1057.

Research output: Contribution to journalArticle

Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, HA, Bomble, YJ, Bufton, JC, Bullock, AN, Caba, C, Cao, H, Davies, OR, Desfosses, A, Dunne, M, Fidelis, K, Goulding, CW, Gurusaran, M, Gutsche, I, Harding, CJ, Hartmann, MD, Hayes, CS, Joachimiak, A, Leiman, PG, Loppnau, P, Lovering, AL, Lunin, VV, Michalska, K, Mir-Sanchis, I, Mitra, AK, Moult, J, Phillips, GN, Pinkas, DM, Rice, PA, Tong, Y, Topf, M, Walton, JD & Schwede, T 2019, 'Target highlights in CASP13: Experimental target structures through the eyes of their authors', Proteins: Structure, Function and Bioinformatics, vol. 87, no. 12, pp. 1037-1057. https://doi.org/10.1002/prot.25805
Lepore, Rosalba ; Kryshtafovych, Andriy ; Alahuhta, Markus ; Veraszto, Harshul A. ; Bomble, Yannick J. ; Bufton, Joshua C. ; Bullock, Alex N. ; Caba, Cody ; Cao, Hongnan ; Davies, Owen R. ; Desfosses, Ambroise ; Dunne, Matthew ; Fidelis, Krzysztof ; Goulding, Celia W. ; Gurusaran, Manickam ; Gutsche, Irina ; Harding, Christopher J. ; Hartmann, Marcus D. ; Hayes, Christopher S. ; Joachimiak, Andrzej ; Leiman, Petr G. ; Loppnau, Peter ; Lovering, Andrew L. ; Lunin, Vladimir V. ; Michalska, Karolina ; Mir-Sanchis, Ignacio ; Mitra, A. K. ; Moult, John ; Phillips, George N. ; Pinkas, Daniel M. ; Rice, Phoebe A. ; Tong, Yufeng ; Topf, Maya ; Walton, Jonathan D. ; Schwede, Torsten. / Target highlights in CASP13 : Experimental target structures through the eyes of their authors. In: Proteins: Structure, Function and Bioinformatics. 2019 ; Vol. 87, No. 12. pp. 1037-1057.
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