@inbook{b18fb0fe44994d9f83950aa3782a79aa,
title = "Tau oligomers as pathogenic seeds: Preparation and propagation in vitro and in vivo",
abstract = "Tau oligomers have been shown to be the main toxic tau species in a number of neurodegenerative disorders. In order to study tau oligomers both in vitro and in vivo, we have established methods for the reliable preparation, isolation, and detection of tau oligomers. Methods for the seeding of tau oligomers, isolation of tau oligomers from tissue, and detection of tau oligomers using tau oligomer-specific antibodies by biochemical and immunohistochemical methods are detailed below.",
keywords = "Amyloid seeding, Tau oligomer isolation, Tau oligomers, Tauopathies",
author = "Gerson, {Julia E.} and Urmi Sengupta and Rakez Kayed",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2017. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2017",
doi = "10.1007/978-1-4939-6598-4_9",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "141--157",
booktitle = "Methods in Molecular Biology",
}