Taurine Requirement with Parenteral Nutrition

To the Editor: The interesting paper by Geggel et al. (Jan. 17 issue)¹ documents an important role for taurine supplementation in children given long-term total parenteral nutrition at home. However, a question arises regarding the dose of taurine used in the investigation. The authors give no information about how they arrived at the doses of taurine they decided to give (12 mmol per liter, or 1.5 to 2.25 g per day). This dose is considerably higher than that available either in a current commercially available solution — 1.2 mmol per liter, recommended to deliver 150 μmol per kilogram of body.