TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells

Keyphrases

• TAR DNA-binding Protein 43 (TDP-43) 100%
• Schwann Cells 100%
• Nerve Conduction Velocity 100%
• Cryptic Exon 100%
• Paranodal Junction 100%
• Junction Assembly 100%
• Neurofascin 33%
• Paranode 33%
• Central Nervous System 11%
• Glial Cells 11%
• Loss Function 11%
• Cell Adhesion Molecules 11%
• Nerve Conduction 11%
• Non-cell Autonomous 11%
• Motor Deficits 11%
• Oligodendrocyte 11%
• Paranodal 11%
• Nonsense-mediated Decay 11%
• Saltatory Conduction 11%
• Peripheral Nerve Conduction 11%

Neuroscience

• Exon 100%
• Nerve Conduction 100%
• Schwann Cell 100%
• Messenger RNA 66%
• Peripheral Nerve 33%
• Central Nervous System 33%
• Microglia 33%
• Oligodendrocyte 33%
• Cell Adhesion Proteins 33%
• Nonsense Mediated mRNA Decay 33%