Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease

Bruce L. Miller, Ismael Mena, James Daly, Robert J. Giomblli, Mark A. Goldberg, Ire Lesser, Karen Garrett, Javier Villanueva-Meyer, Ching Kuan Liu

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Single-phoion emission computerized tomography demonstrates temporal-parietal (TP) hypoperfusion in many patients with Alzheimer’s disease (AD). However, the specificity of these changes has not yet been determined. We have found TP hypoperfusion in five groups of patients including I patient with normal aging. 6 with sleep apnea. I with posthypoxic dementia. 5 with multi-infarct dementia and 2 with ‘pseudo’ TP hypoperfusion with frontal seizures. These findings suggest that the TP cortex may be particularly sensitive to hypoxia and/or hypotension and that hypoperfusion to TP Cortex is not specific to AD.

Original languageEnglish (US)
Pages (from-to)41-45
Number of pages5
JournalDementia and Geriatric Cognitive Disorders
Volume1
Issue number1
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

Fingerprint

Single-Photon Emission-Computed Tomography
Alzheimer Disease
Parietal Lobe
Temporal Lobe
Multi-Infarct Dementia
Emission-Computed Tomography
Sleep Apnea Syndromes
Hypotension
Dementia
Seizures

Keywords

  • <sup>133</sup>Xe-<sup>99m</sup>TC
  • Aging
  • Hexamethylpropyleneamine oxime
  • Posthypoxia
  • Single-photon emission computerized tomography
  • Sleep apnea

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

Cite this

Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease. / Miller, Bruce L.; Mena, Ismael; Daly, James; Giomblli, Robert J.; Goldberg, Mark A.; Lesser, Ire; Garrett, Karen; Villanueva-Meyer, Javier; Liu, Ching Kuan.

In: Dementia and Geriatric Cognitive Disorders, Vol. 1, No. 1, 01.01.1990, p. 41-45.

Research output: Contribution to journalArticle

Miller, BL, Mena, I, Daly, J, Giomblli, RJ, Goldberg, MA, Lesser, I, Garrett, K, Villanueva-Meyer, J & Liu, CK 1990, 'Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease', Dementia and Geriatric Cognitive Disorders, vol. 1, no. 1, pp. 41-45. https://doi.org/10.1159/000107118
Miller, Bruce L. ; Mena, Ismael ; Daly, James ; Giomblli, Robert J. ; Goldberg, Mark A. ; Lesser, Ire ; Garrett, Karen ; Villanueva-Meyer, Javier ; Liu, Ching Kuan. / Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease. In: Dementia and Geriatric Cognitive Disorders. 1990 ; Vol. 1, No. 1. pp. 41-45.
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