Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease

Bruce L. Miller, Ismael Mena, James Daly, Robert J. Giomblli, Mark A. Goldberg, Ire Lesser, Karen Garrett, Javier Villanueva-Meyer, Ching Kuan Liu

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Single-phoion emission computerized tomography demonstrates temporal-parietal (TP) hypoperfusion in many patients with Alzheimer’s disease (AD). However, the specificity of these changes has not yet been determined. We have found TP hypoperfusion in five groups of patients including I patient with normal aging. 6 with sleep apnea. I with posthypoxic dementia. 5 with multi-infarct dementia and 2 with ‘pseudo’ TP hypoperfusion with frontal seizures. These findings suggest that the TP cortex may be particularly sensitive to hypoxia and/or hypotension and that hypoperfusion to TP Cortex is not specific to AD.

Original languageEnglish (US)
Pages (from-to)41-45
Number of pages5
JournalDementia and Geriatric Cognitive Disorders
Volume1
Issue number1
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

Keywords

  • <sup>133</sup>Xe-<sup>99m</sup>TC
  • Aging
  • Hexamethylpropyleneamine oxime
  • Posthypoxia
  • Single-photon emission computerized tomography
  • Sleep apnea

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Temporal-parietal hypoperfusion with single-photon emission computerized tomography in conditions other than alzheimer’s disease'. Together they form a unique fingerprint.

Cite this