Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization

James Meek; Savannah Fletcher; C. Heath Gauss; Sam Bezold; Daniel Borja-Cacho; Mary Meek

doi:10.1016/j.jvir.2019.01.003

Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization

James Meek, Savannah Fletcher, C. Heath Gauss, Sam Bezold, Daniel Borja-Cacho, Mary Meek

Radiology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.

Original language	English (US)
Pages (from-to)	1201-1206
Number of pages	6
Journal	Journal of Vascular and Interventional Radiology
Volume	30
Issue number	8
DOIs	https://doi.org/10.1016/j.jvir.2019.01.003
State	Published - Aug 2019

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.jvir.2019.01.003

Cite this

@article{ad75c651987d46d680604fba0a380f37,

title = "Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization",

abstract = "This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.",

author = "James Meek and Savannah Fletcher and Gauss, {C. Heath} and Sam Bezold and Daniel Borja-Cacho and Mary Meek",

note = "Publisher Copyright: {\textcopyright} 2019 SIR",

year = "2019",

month = aug,

doi = "10.1016/j.jvir.2019.01.003",

language = "English (US)",

volume = "30",

pages = "1201--1206",

journal = "Journal of Vascular and Interventional Radiology",

issn = "1051-0443",

publisher = "Elsevier Inc.",

number = "8",

}

TY - JOUR

T1 - Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization

AU - Meek, James

AU - Fletcher, Savannah

AU - Gauss, C. Heath

AU - Bezold, Sam

AU - Borja-Cacho, Daniel

AU - Meek, Mary

PY - 2019/8

Y1 - 2019/8

N2 - This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.

AB - This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.

UR - http://www.scopus.com/inward/record.url?scp=85066248119&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066248119&partnerID=8YFLogxK

U2 - 10.1016/j.jvir.2019.01.003

DO - 10.1016/j.jvir.2019.01.003

M3 - Article

C2 - 31155499

AN - SCOPUS:85066248119

SN - 1051-0443

VL - 30

SP - 1201

EP - 1206

JO - Journal of Vascular and Interventional Radiology

JF - Journal of Vascular and Interventional Radiology

IS - 8

ER -

Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this