TY - JOUR
T1 - Temporary Balloon Occlusion for Hepatic Arterial Flow Redistribution during Yttrium-90 Radioembolization
AU - Meek, James
AU - Fletcher, Savannah
AU - Gauss, C. Heath
AU - Bezold, Sam
AU - Borja-Cacho, Daniel
AU - Meek, Mary
N1 - Funding Information:
The authors thank Donna Ashlock and the University of Arkansas for Medical Sciences Radiology Department for their invaluable assistance in the production of this manuscript and medical writer Madison Hedrick, MA, for her overall assistance and input regarding the manuscript.
Publisher Copyright:
© 2019 SIR
PY - 2019/8
Y1 - 2019/8
N2 - This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.
AB - This case series describes an approach for radiation segmentectomy–style treatment of hepatic tumors fed by arteries unsuitable for catheterization. The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach. In each case, a balloon microcatheter was used to temporarily redistribute intrahepatic flow during infusion for enhanced radioembolic agent delivery to the tumor. A median of 199 Gy was delivered to a median of 3% of total liver volume. Based on modified Response Evaluation Criteria In Solid Tumors, 11 cases had complete responses and 6 had partial responses.
UR - http://www.scopus.com/inward/record.url?scp=85066248119&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066248119&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2019.01.003
DO - 10.1016/j.jvir.2019.01.003
M3 - Article
C2 - 31155499
AN - SCOPUS:85066248119
SN - 1051-0443
VL - 30
SP - 1201
EP - 1206
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 8
ER -