Term maternal and neonatal complications of acute chorioamnionitis

John C. Hauth, Larry C. Gilstrap, Gary D.V. Hankins, Karen D. Connor

Research output: Contribution to journalArticlepeer-review

132 Scopus citations


One hundred and three women who developed acute chorioamnionitis at 37 weeks' gestation or beyond were studied retrospectively. Clinical findings included fever (99.2%), fetal (82%) and maternal (19.4%) tachycardia, uterine tenderness (16.5%), and foul-smelling amniotic fluid (8.7%). Three of the 46 women who underwent cesarean section subsequently required addition of a second or third antibiotic for serious pelvic infection, whereas two had a subcutaneous wound infection requiring open drainage. Importantly, between zero and ten hours of the diagnosis of chorioamnionitis, a critical time interval where delivery impacted on neonatal infectious morbidity was not identified. Additionally, in the initial 24 hours after rupture of the fetal membranes there was no association between fetal, neonatal, or maternal complications versus duration of membrane rupture. These data suggest that immediate operative delivery of term gestations complicated by acute chorioamnionitis will not reduce neonatal morbidity.

Original languageEnglish (US)
Pages (from-to)59-62
Number of pages4
JournalObstetrics and gynecology
Issue number1
StatePublished - Jul 1985
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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