The adenosine wedge: A new structural motif in ribosomal RNA

Matthieu G. Gagnon, Sergey V. Steinberg

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary structure of the motif. Published by Cold Spring Harbor Laboratory Press.

Original languageEnglish (US)
Pages (from-to)375-381
Number of pages7
Issue number2
StatePublished - Feb 2010
Externally publishedYes


  • A-minor
  • Along-groove packing motif
  • RNA motif
  • RNA structure
  • Ribosomal RNA

ASJC Scopus subject areas

  • Molecular Biology


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