The caliciviruses

Umesh Katpally, Thomas J. Smith

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The caliciviruses are by far themajor cause of non-bacterial gastroenteritis, highly infectious, and have a rapid and severe onset of symptoms. Studies on this family of viruses have been hampered by the lack of animal model and tissue culture system. However, recent advances in protein expression systems and the development of a mouse norovirus animal model has led to rapid advances in our understanding of these viruses with regard to structure and the host immune response. Our current understanding of this important family of viruses is reviewed here.

Original languageEnglish (US)
Pages (from-to)23-41
Number of pages19
JournalCurrent topics in microbiology and immunology
Volume343
Issue number1
DOIs
StatePublished - Dec 1 2010
Externally publishedYes

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)

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