Abstract
Translational science requires that scientists from multiple disciplines work together to improve the prevention, diagnosis, and treatment of human disease. Although a literature exists on the design and management of multidisciplinary teams, little has been written on multidisciplinary translational teams (MTTs). MTTs are distinct hybrid entities, with goals taken from both industry and academic models. We identified 30 design factors in 10 domains from a literature survey relevant to our MTT model: specific goals, structures, and processes. These dimensions were adapted to our own institutional environment in the selection and management of 11 MTTs that exploited resources of University of Texas Medical Branch (UTMB) Clinical and Translational Sciences Awards (CTSA). Case illustrations of two specific MTTs illustrate some of the challenges encountered and opportunities realized in terms of education and scientific advances. Network depiction of disciplinarity indicated that CTSA KRs and CTSA leadership contributed to discipline diversity especially in small (or nascent) MTTs. A separate depiction of MTT-KR utilization indicated that data analysis, translational technologies, and novel methods were heavily utilized by MTTs, whereas other KRs contributed significant effort to infrastructure development. We conclude that the CTSA can provide a rich, infrastructural framework and scientific environment for the development of successful MTTs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 60-71 |
| Number of pages | 12 |
| Journal | Clinical and Translational Science |
| Volume | 6 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2013 |
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Keywords
- Multidisciplinary teams
- Team science
- Translational research
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Neuroscience(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams. / Calhoun, William; Wooten, Kevin; Bhavnani, Suresh; Anderson, Karl; Freeman, Jean; Brasier, Allan R.
In: Clinical and Translational Science, Vol. 6, No. 1, 02.2013, p. 60-71.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams
AU - Calhoun, William
AU - Wooten, Kevin
AU - Bhavnani, Suresh
AU - Anderson, Karl
AU - Freeman, Jean
AU - Brasier, Allan R.
PY - 2013/2
Y1 - 2013/2
N2 - Translational science requires that scientists from multiple disciplines work together to improve the prevention, diagnosis, and treatment of human disease. Although a literature exists on the design and management of multidisciplinary teams, little has been written on multidisciplinary translational teams (MTTs). MTTs are distinct hybrid entities, with goals taken from both industry and academic models. We identified 30 design factors in 10 domains from a literature survey relevant to our MTT model: specific goals, structures, and processes. These dimensions were adapted to our own institutional environment in the selection and management of 11 MTTs that exploited resources of University of Texas Medical Branch (UTMB) Clinical and Translational Sciences Awards (CTSA). Case illustrations of two specific MTTs illustrate some of the challenges encountered and opportunities realized in terms of education and scientific advances. Network depiction of disciplinarity indicated that CTSA KRs and CTSA leadership contributed to discipline diversity especially in small (or nascent) MTTs. A separate depiction of MTT-KR utilization indicated that data analysis, translational technologies, and novel methods were heavily utilized by MTTs, whereas other KRs contributed significant effort to infrastructure development. We conclude that the CTSA can provide a rich, infrastructural framework and scientific environment for the development of successful MTTs.
AB - Translational science requires that scientists from multiple disciplines work together to improve the prevention, diagnosis, and treatment of human disease. Although a literature exists on the design and management of multidisciplinary teams, little has been written on multidisciplinary translational teams (MTTs). MTTs are distinct hybrid entities, with goals taken from both industry and academic models. We identified 30 design factors in 10 domains from a literature survey relevant to our MTT model: specific goals, structures, and processes. These dimensions were adapted to our own institutional environment in the selection and management of 11 MTTs that exploited resources of University of Texas Medical Branch (UTMB) Clinical and Translational Sciences Awards (CTSA). Case illustrations of two specific MTTs illustrate some of the challenges encountered and opportunities realized in terms of education and scientific advances. Network depiction of disciplinarity indicated that CTSA KRs and CTSA leadership contributed to discipline diversity especially in small (or nascent) MTTs. A separate depiction of MTT-KR utilization indicated that data analysis, translational technologies, and novel methods were heavily utilized by MTTs, whereas other KRs contributed significant effort to infrastructure development. We conclude that the CTSA can provide a rich, infrastructural framework and scientific environment for the development of successful MTTs.
KW - Multidisciplinary teams
KW - Team science
KW - Translational research
UR - http://www.scopus.com/inward/record.url?scp=84873724045&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84873724045&partnerID=8YFLogxK
U2 - 10.1111/cts.12004
DO - 10.1111/cts.12004
M3 - Article
C2 - 23399092
AN - SCOPUS:84873724045
VL - 6
SP - 60
EP - 71
JO - Clinical and Translational Science
JF - Clinical and Translational Science
SN - 1752-8054
IS - 1
ER -