The CUBE Technique

Continuous Ultrasound-Guided Breast Excision

Evan Tummel, Richard Betzold, Kristalyn Gallagher, Vicki Klimberg

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Margin negativity is a critical endpoint in breast-conserving surgery. Despite advances in technology, there is up to a 40 % positive margin rate in lumpectomy specimens, which results in a twofold increase in ipsilateral breast tumor recurrence. We have developed a new method for lumpectomy that could improve margin negativity. Methods: A novel method for partial mastectomy was developed using ultrasound to perform dissection of breast specimens in real time. Continuous ultrasound-guided breast excision (CUBE) was first tested on gel models and subsequently implemented in vivo. The step-by-step method for this technique was performed on 12 successive patients who had ultrasound-detectable lesions. Results: Twelve patients underwent lumpectomy for cancer using the CUBE technique. All patients had negative margins on final pathology. Three patients who had close margins on ex vivo ultrasound evaluation had additional shave margins taken, resulting in negative final margins. Conclusions: The CUBE technique is a novel technique that allows for dissection of breast lesions with continuous visualization of margins. This facilitates real-time adjustments to ensure margin negativity. Preliminary data is promising, but further research is needed for confirmation.

Original languageEnglish (US)
Pages (from-to)3354-3355
Number of pages2
JournalAnnals of Surgical Oncology
Volume21
Issue number10
DOIs
StatePublished - 2014
Externally publishedYes

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Segmental Mastectomy
Breast
Dissection
Gels
Pathology
Breast Neoplasms
Technology
Recurrence
Research
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Oncology
  • Medicine(all)

Cite this

The CUBE Technique : Continuous Ultrasound-Guided Breast Excision. / Tummel, Evan; Betzold, Richard; Gallagher, Kristalyn; Klimberg, Vicki.

In: Annals of Surgical Oncology, Vol. 21, No. 10, 2014, p. 3354-3355.

Research output: Contribution to journalArticle

Tummel, Evan ; Betzold, Richard ; Gallagher, Kristalyn ; Klimberg, Vicki. / The CUBE Technique : Continuous Ultrasound-Guided Breast Excision. In: Annals of Surgical Oncology. 2014 ; Vol. 21, No. 10. pp. 3354-3355.
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