Keyphrases
Inflammatory Cytokines
100%
Dihydroorotate Dehydrogenase Inhibitor
100%
SARS-CoV-2 Replication
100%
PTC299
100%
Interleukin-17 (IL-17)
50%
COVID-19
50%
Dihydroorotate Dehydrogenase (DHODH)
50%
Virus
16%
Vascular Endothelial Growth Factor
16%
Inflammation
16%
Tissue Culture
16%
RNA Virus
16%
Interleukin-6
16%
Rate-limiting Enzyme
16%
Inhibitory Activity
16%
Dose Effect
16%
Pharmacokinetics
16%
Cytokine Production
16%
Orally Bioavailable
16%
Selectivity Index
16%
Safety Profile
16%
Tissue Culture Model
16%
Ebola Virus
16%
COVID-19 Pandemic
16%
Potent Inhibitor
16%
EC50
16%
Immunosuppressive Cytokines
16%
Human Safety
16%
Biosynthesis Pathway
16%
Pyrimidine Biosynthesis
16%
Advanced Illness
16%
Anti-SARS-CoV-2 Activity
16%
Medicine and Dentistry
Inflammatory Cytokine
100%
Severe Acute Respiratory Syndrome Coronavirus 2
100%
Dihydroorotate Dehydrogenase Inhibitor
100%
Ptc 299
100%
Interleukin 17
50%
Dihydroorotate Dehydrogenase
50%
COVID-19
33%
Vasculotropin
16%
Pharmacokinetics
16%
Cytokine
16%
Cytokine Production
16%
Fulminant
16%
Interleukin 6
16%
Ebolavirus
16%
Nucleotide Metabolism
16%
Selectivity Index
16%
Pyrimidine Nucleotide
16%
Diseases
16%
Virus
16%
RNA Virus
16%
Pharmacology, Toxicology and Pharmaceutical Science
Cytokine
100%
SARS Coronavirus
100%
Dihydroorotate Dehydrogenase Inhibitor
100%
Ptc 299
100%
Interleukin 17
50%
Dihydroorotate Dehydrogenase
50%
Diseases
50%
Coronavirinae
33%
Pyrimidine Nucleotide
16%
Inflammation
16%
Vasculotropin
16%
Interleukin 6
16%
Ebola Virus
16%
Pharmacokinetics
16%
EC50
16%
RNA Virus
16%
Immunology and Microbiology
Inflammatory Cytokine
100%
Severe Acute Respiratory Syndrome Coronavirus 2
100%
Ptc 299
100%
Replication
100%
Interleukin 17
50%
Tissue Culture
33%
COVID-19
33%
Cytokine
16%
RNA Virus
16%
Pharmacokinetics
16%
Cytokine Production
16%
Vasculotropin
16%
Ebola Virus
16%
Interleukin 6
16%
EC50
16%
Nucleotide Metabolism
16%
Selectivity Index
16%
Virus
16%
Neuroscience
SARS Coronavirus
100%
Ptc 299
100%
Dihydroorotate Dehydrogenase
100%
Cytokine
100%
Interleukin 17
50%
Coronavirinae
33%
Coronavirus
33%
RNA Virus
16%
Vascular Endothelial Growth Factor
16%
Cytokine Production
16%
Interleukin 6
16%
Anabolism
16%
Ebolavirus
16%
Pyrimidine Nucleotide
16%
Pharmacokinetics
16%