The effect of adriamycin on repair of sublethal damage and slow repair in irradiated mouse lung

J. L. Redpath, E. Zabilansky, M. Colman

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The interaction of Adriamycin with radiation damage in the mouse lung has been shown to disappear with the same kinetics as those for the slow repair of such radiation damage. Split-dose experiments have demonstrated that Adriamycin inhibits this slow repair process whereas the drug has no effect on the repair of sublethal damage in irradiated mouse lung.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalInternational Journal of Radiation Biology
Volume39
Issue number2
DOIs
StatePublished - 1981
Externally publishedYes

Fingerprint

doxorubicin
radiation damage
Doxorubicin
lungs
mice
Repair
Radiation damage
Radiation
damage
Lung
drugs
kinetics
dosage
Dosimetry
Pharmaceutical Preparations
Kinetics
interactions
Experiments

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Agricultural and Biological Sciences (miscellaneous)
  • Nuclear Energy and Engineering
  • Radiation

Cite this

The effect of adriamycin on repair of sublethal damage and slow repair in irradiated mouse lung. / Redpath, J. L.; Zabilansky, E.; Colman, M.

In: International Journal of Radiation Biology, Vol. 39, No. 2, 1981, p. 157-161.

Research output: Contribution to journalArticle

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