The effect of cytosine arabinoside on platelet aggregation

Robert G. Gagliano, Anne M. Terrebonne, Jack B. Alperin, John J. Costanzi

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4 Scopus citations

Abstract

Platelet aggregation induced by ADP, collagen, epinephrine, and thrombin was studied in patients with acute leukemia in complete remission, before and after a continuous 5‐day intravenous infusion of cytosine arabinoside at a dose of 100 mg/m2 per day. Aggregation was also measured in normal subjects with cytosine arabinoside added in vitro. Cytosine arabinoside had no significant effect on platelet aggregation after either in vitro or in vivo administration.

Original languageEnglish (US)
Pages (from-to)2247-2249
Number of pages3
JournalCancer
Volume38
Issue number6
DOIs
StatePublished - Dec 1976

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Gagliano, R. G., Terrebonne, A. M., Alperin, J. B., & Costanzi, J. J. (1976). The effect of cytosine arabinoside on platelet aggregation. Cancer, 38(6), 2247-2249. https://doi.org/10.1002/1097-0142(197612)38:6<2247::AID-CNCR2820380609>3.0.CO;2-Z