The effect of cytosine arabinoside on platelet aggregation

Robert G. Gagliano, Anne M. Terrebonne, Jack B. Alperin, John J. Costanzi

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Platelet aggregation induced by ADP, collagen, epinephrine, and thrombin was studied in patients with acute leukemia in complete remission, before and after a continuous 5‐day intravenous infusion of cytosine arabinoside at a dose of 100 mg/m2 per day. Aggregation was also measured in normal subjects with cytosine arabinoside added in vitro. Cytosine arabinoside had no significant effect on platelet aggregation after either in vitro or in vivo administration.

Original languageEnglish (US)
Pages (from-to)2247-2249
Number of pages3
Issue number6
StatePublished - Dec 1976
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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