The effect of metastatic site and decade of diagnosis on the individual burden of metastatic melanoma: Contemporary estimates of average years of life lost

April K S Salama, Nicole De Rosa, Randall P. Scheri, James E. Herndon, Douglas Tyler, Jennifer Marcello, Scott K. Pruitt, Amy P. Abernethy

Research output: Contribution to journalArticle

7 Scopus citations


Objectives: Metastatic melanoma (MM) is a leading cause of years of life lost due to malignancy. This study aimed to identify the average years of life lost (AYLL) in MM patients. Methods: MM patients were identified from a prospectively maintained database, and a linear model predicting AYLL was developed. Results: Between 1970 and 1999, 4,774 patients diagnosed with MM died. The AYLL was 23.2 years. AYLL remained stable across three decades. Conclusions: AYLL for MM is greater than 20 years, and has not improved. This burden underscores the need for continued research and access to funding for this disease.

Original languageEnglish (US)
Pages (from-to)637-641
Number of pages5
JournalCancer Investigation
Issue number9
StatePublished - Nov 2012
Externally publishedYes



  • Life expectancy
  • Melanoma
  • Mortality
  • Potential years of life lost
  • Survival

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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