The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy

Sandra L. Wong, Michael J. Edwards, Celia Chao, Todd M. Tuttle, R. Dirk Noyes, David J. Carlson, Alison L. Laidley, Terre Q. McGlothin, Philip B. Ley, C. Matthew Brown, Rebecca L. Glaser, Robert E. Pennington, Peter S. Turk, Diana Simpson, Kelly M. McMasters

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

It has been suggested that sentinel lymph node (SLN) biopsy for breast cancer may be less accurate after excisional biopsy of the primary tumor compared with core needle biopsy. Furthermore, some have suggested an improved ability to identify the SLN when total mastectomy is performed compared with lumpectomy. This analysis was performed to determine the impact of the type of breast biopsy (needle vs. excisional) or definitive surgical procedure (lumpectomy vs. mastectomy) on the accuracy of SLN biopsy. Methods: The University of Louisville Breast Cancer Sentinel Lymph Node Study is a prospective multi-institutional study. Patients with clinical stage T1-2, NO breast cancer were eligible. All patients underwent SLN biopsy and completion level I/II axillary dissection. Statistical comparison was performed by X2 analysis. Results: A total of 2206 patients were enrolled in the study. There were no statistically significant differences in SLN identification rate or false-negative rate between patients undergoing excisional versus needle biopsy. The SLN identification and false-negative rates also were not statistically different between patients who had total mastectomy compared with those who had a lumpectomy. Conclusions: Excisional biopsy does not significantly affect the accuracy of SLN biopsy, nor does the type of definitive surgical procedure.

Original languageEnglish (US)
Pages (from-to)272-277
Number of pages6
JournalAnnals of Surgical Oncology
Volume9
Issue number3
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Sentinel Lymph Node Biopsy
Breast
Segmental Mastectomy
Biopsy
Simple Mastectomy
Needle Biopsy
Breast Neoplasms
Large-Core Needle Biopsy
Mastectomy
Dissection
Sentinel Lymph Node
Neoplasms

Keywords

  • Axillary node dissection
  • Breast cancer
  • Excisional biopsy
  • Sentinel lymph node

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy. / Wong, Sandra L.; Edwards, Michael J.; Chao, Celia; Tuttle, Todd M.; Dirk Noyes, R.; Carlson, David J.; Laidley, Alison L.; McGlothin, Terre Q.; Ley, Philip B.; Matthew Brown, C.; Glaser, Rebecca L.; Pennington, Robert E.; Turk, Peter S.; Simpson, Diana; McMasters, Kelly M.

In: Annals of Surgical Oncology, Vol. 9, No. 3, 2002, p. 272-277.

Research output: Contribution to journalArticle

Wong, SL, Edwards, MJ, Chao, C, Tuttle, TM, Dirk Noyes, R, Carlson, DJ, Laidley, AL, McGlothin, TQ, Ley, PB, Matthew Brown, C, Glaser, RL, Pennington, RE, Turk, PS, Simpson, D & McMasters, KM 2002, 'The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy', Annals of Surgical Oncology, vol. 9, no. 3, pp. 272-277. https://doi.org/10.1245/aso.2002.9.3.272
Wong, Sandra L. ; Edwards, Michael J. ; Chao, Celia ; Tuttle, Todd M. ; Dirk Noyes, R. ; Carlson, David J. ; Laidley, Alison L. ; McGlothin, Terre Q. ; Ley, Philip B. ; Matthew Brown, C. ; Glaser, Rebecca L. ; Pennington, Robert E. ; Turk, Peter S. ; Simpson, Diana ; McMasters, Kelly M. / The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy. In: Annals of Surgical Oncology. 2002 ; Vol. 9, No. 3. pp. 272-277.
@article{42bc031037aa4004828032bd46ac7430,
title = "The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy",
abstract = "It has been suggested that sentinel lymph node (SLN) biopsy for breast cancer may be less accurate after excisional biopsy of the primary tumor compared with core needle biopsy. Furthermore, some have suggested an improved ability to identify the SLN when total mastectomy is performed compared with lumpectomy. This analysis was performed to determine the impact of the type of breast biopsy (needle vs. excisional) or definitive surgical procedure (lumpectomy vs. mastectomy) on the accuracy of SLN biopsy. Methods: The University of Louisville Breast Cancer Sentinel Lymph Node Study is a prospective multi-institutional study. Patients with clinical stage T1-2, NO breast cancer were eligible. All patients underwent SLN biopsy and completion level I/II axillary dissection. Statistical comparison was performed by X2 analysis. Results: A total of 2206 patients were enrolled in the study. There were no statistically significant differences in SLN identification rate or false-negative rate between patients undergoing excisional versus needle biopsy. The SLN identification and false-negative rates also were not statistically different between patients who had total mastectomy compared with those who had a lumpectomy. Conclusions: Excisional biopsy does not significantly affect the accuracy of SLN biopsy, nor does the type of definitive surgical procedure.",
keywords = "Axillary node dissection, Breast cancer, Excisional biopsy, Sentinel lymph node",
author = "Wong, {Sandra L.} and Edwards, {Michael J.} and Celia Chao and Tuttle, {Todd M.} and {Dirk Noyes}, R. and Carlson, {David J.} and Laidley, {Alison L.} and McGlothin, {Terre Q.} and Ley, {Philip B.} and {Matthew Brown}, C. and Glaser, {Rebecca L.} and Pennington, {Robert E.} and Turk, {Peter S.} and Diana Simpson and McMasters, {Kelly M.}",
year = "2002",
doi = "10.1245/aso.2002.9.3.272",
language = "English (US)",
volume = "9",
pages = "272--277",
journal = "Annals of Surgical Oncology",
issn = "1068-9265",
publisher = "Springer New York",
number = "3",

}

TY - JOUR

T1 - The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy

AU - Wong, Sandra L.

AU - Edwards, Michael J.

AU - Chao, Celia

AU - Tuttle, Todd M.

AU - Dirk Noyes, R.

AU - Carlson, David J.

AU - Laidley, Alison L.

AU - McGlothin, Terre Q.

AU - Ley, Philip B.

AU - Matthew Brown, C.

AU - Glaser, Rebecca L.

AU - Pennington, Robert E.

AU - Turk, Peter S.

AU - Simpson, Diana

AU - McMasters, Kelly M.

PY - 2002

Y1 - 2002

N2 - It has been suggested that sentinel lymph node (SLN) biopsy for breast cancer may be less accurate after excisional biopsy of the primary tumor compared with core needle biopsy. Furthermore, some have suggested an improved ability to identify the SLN when total mastectomy is performed compared with lumpectomy. This analysis was performed to determine the impact of the type of breast biopsy (needle vs. excisional) or definitive surgical procedure (lumpectomy vs. mastectomy) on the accuracy of SLN biopsy. Methods: The University of Louisville Breast Cancer Sentinel Lymph Node Study is a prospective multi-institutional study. Patients with clinical stage T1-2, NO breast cancer were eligible. All patients underwent SLN biopsy and completion level I/II axillary dissection. Statistical comparison was performed by X2 analysis. Results: A total of 2206 patients were enrolled in the study. There were no statistically significant differences in SLN identification rate or false-negative rate between patients undergoing excisional versus needle biopsy. The SLN identification and false-negative rates also were not statistically different between patients who had total mastectomy compared with those who had a lumpectomy. Conclusions: Excisional biopsy does not significantly affect the accuracy of SLN biopsy, nor does the type of definitive surgical procedure.

AB - It has been suggested that sentinel lymph node (SLN) biopsy for breast cancer may be less accurate after excisional biopsy of the primary tumor compared with core needle biopsy. Furthermore, some have suggested an improved ability to identify the SLN when total mastectomy is performed compared with lumpectomy. This analysis was performed to determine the impact of the type of breast biopsy (needle vs. excisional) or definitive surgical procedure (lumpectomy vs. mastectomy) on the accuracy of SLN biopsy. Methods: The University of Louisville Breast Cancer Sentinel Lymph Node Study is a prospective multi-institutional study. Patients with clinical stage T1-2, NO breast cancer were eligible. All patients underwent SLN biopsy and completion level I/II axillary dissection. Statistical comparison was performed by X2 analysis. Results: A total of 2206 patients were enrolled in the study. There were no statistically significant differences in SLN identification rate or false-negative rate between patients undergoing excisional versus needle biopsy. The SLN identification and false-negative rates also were not statistically different between patients who had total mastectomy compared with those who had a lumpectomy. Conclusions: Excisional biopsy does not significantly affect the accuracy of SLN biopsy, nor does the type of definitive surgical procedure.

KW - Axillary node dissection

KW - Breast cancer

KW - Excisional biopsy

KW - Sentinel lymph node

UR - http://www.scopus.com/inward/record.url?scp=0036213876&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036213876&partnerID=8YFLogxK

U2 - 10.1245/aso.2002.9.3.272

DO - 10.1245/aso.2002.9.3.272

M3 - Article

VL - 9

SP - 272

EP - 277

JO - Annals of Surgical Oncology

JF - Annals of Surgical Oncology

SN - 1068-9265

IS - 3

ER -