The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study

Abolghasem Jouyban; Mohammadali M. Shoja; Mohammad Reza Ardalan; Maryam Khoubnasabjafari; Alireza Sadighi; R. Shane Tubbs; Paul S. Agutter; Kamyar Ghabili

The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study

Abolghasem Jouyban, Mohammadali M. Shoja, Mohammad Reza Ardalan, Maryam Khoubnasabjafari, Alireza Sadighi, R. Shane Tubbs, Paul S. Agutter, Kamyar Ghabili

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

There has been no investigation on the efficacy of quince extracts (Cydonia oblonga Miller) against hyperlipidemia-induced renal injury. In the present study, this hypothesis was evaluated by a histological comparison of kidney tissues from New Zealand white rabbits fed on a cholesterol-rich diet with and without a quince leaf extract supplement. Mild glomerular injury and moderate tubular damage were apparent in all rabbits in disease group. Meanwhile, milder tubular injury was detected in all animals in treatment group. The results were consistent with the hypothesis and suggest that a more extended study would be justified.

Original language	English (US)
Pages (from-to)	5291-5295
Number of pages	5
Journal	Journal of Medicinal Plant Research
Volume	5
Issue number	21
State	Published - Oct 9 2011
Externally published	Yes

Keywords

Cholesterol
Diet
Herb
Kidney
Quince

ASJC Scopus subject areas

Pharmacology
Pharmaceutical Science
Drug Discovery
Plant Science
Complementary and alternative medicine

Cite this

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title = "The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study",

abstract = "There has been no investigation on the efficacy of quince extracts (Cydonia oblonga Miller) against hyperlipidemia-induced renal injury. In the present study, this hypothesis was evaluated by a histological comparison of kidney tissues from New Zealand white rabbits fed on a cholesterol-rich diet with and without a quince leaf extract supplement. Mild glomerular injury and moderate tubular damage were apparent in all rabbits in disease group. Meanwhile, milder tubular injury was detected in all animals in treatment group. The results were consistent with the hypothesis and suggest that a more extended study would be justified.",

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AU - Jouyban, Abolghasem

AU - Shoja, Mohammadali M.

AU - Ardalan, Mohammad Reza

AU - Khoubnasabjafari, Maryam

AU - Sadighi, Alireza

AU - Shane Tubbs, R.

AU - Agutter, Paul S.

AU - Ghabili, Kamyar

PY - 2011/10/9

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N2 - There has been no investigation on the efficacy of quince extracts (Cydonia oblonga Miller) against hyperlipidemia-induced renal injury. In the present study, this hypothesis was evaluated by a histological comparison of kidney tissues from New Zealand white rabbits fed on a cholesterol-rich diet with and without a quince leaf extract supplement. Mild glomerular injury and moderate tubular damage were apparent in all rabbits in disease group. Meanwhile, milder tubular injury was detected in all animals in treatment group. The results were consistent with the hypothesis and suggest that a more extended study would be justified.

AB - There has been no investigation on the efficacy of quince extracts (Cydonia oblonga Miller) against hyperlipidemia-induced renal injury. In the present study, this hypothesis was evaluated by a histological comparison of kidney tissues from New Zealand white rabbits fed on a cholesterol-rich diet with and without a quince leaf extract supplement. Mild glomerular injury and moderate tubular damage were apparent in all rabbits in disease group. Meanwhile, milder tubular injury was detected in all animals in treatment group. The results were consistent with the hypothesis and suggest that a more extended study would be justified.

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KW - Diet

KW - Herb

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The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study

Abstract

Keywords

ASJC Scopus subject areas

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