The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study

Abolghasem Jouyban, Mohammadali Mohajel Shoja, Mohammad Reza Ardalan, Maryam Khoubnasabjafari, Alireza Sadighi, R. Shane Tubbs, Paul S. Agutter, Kamyar Ghabili

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

There has been no investigation on the efficacy of quince extracts (Cydonia oblonga Miller) against hyperlipidemia-induced renal injury. In the present study, this hypothesis was evaluated by a histological comparison of kidney tissues from New Zealand white rabbits fed on a cholesterol-rich diet with and without a quince leaf extract supplement. Mild glomerular injury and moderate tubular damage were apparent in all rabbits in disease group. Meanwhile, milder tubular injury was detected in all animals in treatment group. The results were consistent with the hypothesis and suggest that a more extended study would be justified.

Original languageEnglish (US)
Pages (from-to)5291-5295
Number of pages5
JournalJournal of Medicinal Plant Research
Volume5
Issue number21
StatePublished - Oct 9 2011
Externally publishedYes

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Keywords

  • Cholesterol
  • Diet
  • Herb
  • Kidney
  • Quince

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

Cite this

Jouyban, A., Mohajel Shoja, M., Ardalan, M. R., Khoubnasabjafari, M., Sadighi, A., Shane Tubbs, R., Agutter, P. S., & Ghabili, K. (2011). The effect of quince leaf decoction on renal injury induced by hypercholesterolemia in rabbits: A pilot study. Journal of Medicinal Plant Research, 5(21), 5291-5295.